Technology Process of 7-Octynoic acid methyl ester
There total 1 articles about 7-Octynoic acid methyl ester which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 3 steps
1: sulfuric acid / Reflux
2: sodium hydrogencarbonate; Dess-Martin periodane / dichloromethane / 2 h / 20 °C
3: potassium carbonate / methanol / 4 h / 20 °C / Inert atmosphere
With
sulfuric acid; sodium hydrogencarbonate; potassium carbonate; Dess-Martin periodane;
In
methanol; dichloromethane;
DOI:10.1016/j.tetlet.2019.151510
- Guidance literature:
-
With
triethylamine;
In
tetrahydrofuran;
at 20 ℃;
for 24h;
- Guidance literature:
-
Multi-step reaction with 3 steps
1: LiAlH4 / diethyl ether / 2 h / 0 °C
2: 76 percent / LiNH2, Fe(NO3)3 / tetrahydrofuran; NH3 / 20 h
3: H2 / PtO2 / diethyl ether
With
lithium aluminium tetrahydride; lithium amide; hydrogen; ferric nitrate;
platinum(IV) oxide;
In
tetrahydrofuran; diethyl ether; ammonia;
