butylene chlorohydrin

Base Information

• Chemical Name: butylene chlorohydrin
• CAS No.: 1873-25-2
• Molecular Formula: C4H9ClO
• Molecular Weight: 108.568
• Hs Code.: 2905590090
• Mol file: 1873-25-2.mol

Synonyms:2-Butanol,1-chloro;2-Butanol, 1-chloro-;1-chloro-2-hydroxybutane;1-Chlor-butan-2-ol;Chlormethyl-aethyl-carbinol;1-chloro-2-butanol;Butylenchlorhydrin;1-chloro-butan-2-ol;

Chemical Property of butylene chlorohydrin

Chemical Property:

• Refractive Index: 1.4400
• Boiling Point: 122.94°C (rough estimate)
• PSA: 20.23000
• Density: 1.0680
• LogP: 0.99610

Purity/Quality:

99% ^*data from raw suppliers

1-chlorobutan-2-ol ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of butylene chlorohydrin

There total 20 articles about butylene chlorohydrin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

ethyloxirane (106-88-7) → 1-chloro-butan-2-ol (1873-25-2)

Guidance literature:

With chloro-trimethyl-silane; 3-butyl-1-methyl-1H-imidazol-3-ium hexafluorophosphate; at 20 ℃; for 1h;

DOI:10.1016/j.tetlet.2004.01.042

Reference yield: 71.0%

ethyloxirane (106-88-7) + chloroform (67-66-3,8013-54-5) → 1-chloro-butan-2-ol (1873-25-2)

Guidance literature:

With tetrachloromethane; In N,N-dimethyl-formamide; electroreduction;

DOI:10.1021/jo00214a025

Reference yield: 18.0%

1-butylene (106-98-9,9003-28-5) + acetic acid (64-19-7,77671-22-8) → chloro-1 acetoxy-2 butane (13422-61-2) + 1-chloro-butan-2-ol (1873-25-2) + chloro-2 acetoxy-1 butane (76475-07-5) + N-(1-Chloromethyl-propyl)-4-methyl-benzenesulfonamide

Guidance literature:

With chloroamine-T; at 50 - 60 ℃; for 3h; Yield given. Further byproducts given. Yields of byproduct given;

DOI:10.1016/S0040-4039(00)77816-6

upstream raw materials:

ethyloxirane

2-chloroethanal

diethyl ether

ethylmagnesium bromide

Downstream raw materials:

ethyloxirane

1-chlorobutan-2-one

(+/-)-1-Dimethylamino-2-butanol

benzyl propyl ether

Refernces

• 1、 Das, Biswanath,Venkateswarlu, Katta,Krishnaiah, Maddeboina. "Synthesis of β-chlorohydrins in water". . p. 149 - 152. Retrieved 2007/10/03.
• 2、 Xu, Li-Wen,Li, Lyi,Xia, Chun-Gu,Zhao, Pei-Qing. "Efficient synthesis of chlorohydrins: Ionic liquid promoted ring-opening reaction of epoxides and TMSCl". . p. 2435 - 2438. Retrieved 2007/10/03.