Hydrazine, (2-ethylphenyl)-

Base Information

• Chemical Name: Hydrazine, (2-ethylphenyl)-
• CAS No.: 19275-55-9
• Molecular Formula: C8H12N2
• Molecular Weight: 136.197
• Mol file: 19275-55-9.mol

Synonyms:2-Ethylphenylhydrazinehydrochloride;N-(2-ethylphenyl)hydrazine;2-ethynylphenylhydrazine;2-Hydrazino-1-aethyl-benzol;2-Et-C6H4NHNH2;2-ethylphenylhydrazine;

Chemical Property of Hydrazine, (2-ethylphenyl)-

Chemical Property:

• Melting Point: 102.5-103 °C
• Boiling Point: 247.7±19.0 °C(Predicted)
• PKA: 5.34±0.10(Predicted)
• PSA: 38.05000
• Density: 1.056±0.06 g/cm3(Predicted)
• LogP: 2.30790

Purity/Quality:

99%, ^*data from raw suppliers

(2-Ethylphenyl)hydrazine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Use Description: Hydrazine, specifically (2-ethylphenyl)hydrazine, finds its utility across various fields due to its unique chemical properties. In the pharmaceutical industry, it is employed as a key intermediate in the synthesis of pharmaceutical compounds and agrochemicals. Its versatile reactivity allows for the creation of complex organic molecules, contributing to the development of potential drug candidates. In organic synthesis, (2-ethylphenyl)hydrazine serves as a valuable building block for the production of various organic chemicals, including dyes, polymers, and specialty chemicals used in the manufacturing of adhesives and coatings. Additionally, in the field of analytical chemistry, it is used as a reagent for testing and analyzing various substances. Its role as a versatile chemical precursor and reagent underscores its importance in chemical research and development across different industries.

Technology Process of Hydrazine, (2-ethylphenyl)-

There total 4 articles about Hydrazine, (2-ethylphenyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

1-(2-ethylphenyl)hydrazono-2-oxopropionaldehyde → (2-ethyl-phenyl)-hydrazine (19275-55-9)

Guidance literature:

With hydrogenchloride; hydrazine hydrate; In ethanol; at 95 - 100 ℃; for 8h;

DOI:10.1080/00397919108020835

Reference yield:

2-ethylphenyl tosylate (848170-57-0) → (2-ethyl-phenyl)-hydrazine (19275-55-9)

Guidance literature:

With bis[chloro(1,2,3-trihapto-allylbenzene)palladium(II)]; N-[2-(di(1-adamantyl)phosphino)phenyl]morpholine; hydrazine hydrate; sodium t-butanolate; In toluene; at 65 ℃; for 1h; Inert atmosphere; Glovebox;

DOI:10.1016/j.bmcl.2015.11.022

Reference yield:

→ (2-ethyl-phenyl)-hydrazine (19275-55-9)

Guidance literature:

upstream raw materials:

2-ethylphenyl tosylate

Downstream raw materials:

1-ethyl-2-phenyl-1H-indole

7,8-dimethoxy-2-(2-ethylphenyl)-1(2H)-phthalazinone

2-(2-ethylphenyl)-1(2H)-phthalazinone

2-(2-ethylphenyl)-5-methyl-2,4-dihydropyrazol-3-one

Refernces

• 1、 Gonzalez. "A convenient preparation of 8-ethyl-4,9-dihydro-3H-pyrano[3,4-b]indole-1-one, key intermediate of the antiinflammatory agent Etodolac". . p. 669 - 674. Retrieved 2007/10/02.