N-Acetyl-3-hydroxy-L-tyrosine

Base Information Edit

Chemical Name:N-Acetyl-3-hydroxy-L-tyrosine
CAS No.:19641-90-8
Molecular Formula:C₁₁H₁₃NO₅
Molecular Weight:239.228
Hs Code.:
DSSTox Substance ID:DTXSID10553855
Metabolomics Workbench ID:103377
Nikkaji Number:J685.120G
Wikidata:Q77567961
Mol file:19641-90-8.mol

Synonyms:19641-90-8;N-Acetyl-3-hydroxy-L-tyrosine;N-acetyl-3,4-dihydroxy-L-phenylalanine;L-Tyrosine, N-acetyl-3-hydroxy-;(2S)-2-acetamido-3-(3,4-dihydroxyphenyl)propanoic acid;(2S)-3-(3,4-dihydroxyphenyl)-2-acetamidopropanoic acid;SCHEMBL468823;DTXSID10553855;CHEBI:219544;RGCLHVKCJVVHLN-QMMMGPOBSA-N;EN300-12886430

Suppliers and Price of N-Acetyl-3-hydroxy-L-tyrosine

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of N-Acetyl-3-hydroxy-L-tyrosine Edit

Chemical Property:

XLogP3:-0.2
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:4
Exact Mass:239.07937252
Heavy Atom Count:17
Complexity:294

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=O)NC(CC1=CC(=C(C=C1)O)O)C(=O)O
Isomeric SMILES:CC(=O)N[C@@H](CC1=CC(=C(C=C1)O)O)C(=O)O

Technology Process of N-Acetyl-3-hydroxy-L-tyrosine

There total 8 articles about N-Acetyl-3-hydroxy-L-tyrosine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 28104-71-4,20850-40-2
(S)-(+)-N-Acetyl-3-<3,4-(methylendioxy)phenyl>alanin

: 40332-26-1,40332-27-2,19641-90-8
N-acetyl-3,4-dihydroxy-L-phenylalanine

Guidance literature:: With hydrogenchloride; phenol; for 20h; Heating;

Reference yield: 49.0%

: 59-92-7,90638-38-3
levodopa

: 108-24-7
acetic anhydride

: 40332-26-1,40332-27-2,19641-90-8
N-acetyl-3,4-dihydroxy-L-phenylalanine

Guidance literature:: With water; at 20 ℃; for 2h; Inert atmosphere;
DOI:10.1021/ja106503a

Reference yield:

: 120-57-0,30024-74-9
piperonal

: 40332-26-1,40332-27-2,19641-90-8
N-acetyl-3,4-dihydroxy-L-phenylalanine

Guidance literature:: Multi-step reaction with 4 steps

1: AcONa / 1 h / Heating

2: 1.) MeONa, 2.) H₂ / 2.) 10percent Pd/C / 1.) 10 min, 2.) MeOH, 50 deg C, 2-3 h

3: 97.6 percent / NaOH / H₂O / Alcalase, pH 7.5

4: 80 percent / 20percent aq. HCl, phenol / 20 h / Heating

With hydrogenchloride; sodium hydroxide; hydrogen; sodium methylate; sodium acetate; phenol; palladium on activated charcoal; In water;