hydrazinecarbothioic acid O-methyl ester

Base Information

• Chemical Name: hydrazinecarbothioic acid O-methyl ester
• CAS No.: 19692-07-0
• Molecular Formula: C2H6N2OS
• Molecular Weight: 106.14700
• Mol file: 19692-07-0.mol

Synonyms:O-methyl thiocarbazate;methyl imidothiocarbamate;methoxy thiocarbonyl hydrazine;methoxy thiocarbonylhydrazine;hydrazinecarbothioic acid O-methyl ester;methoxythiocarbonyl hydrazine;

Chemical Property of hydrazinecarbothioic acid O-methyl ester

Chemical Property:

• Melting Point: 72-74 °C
• Boiling Point: 142.0±23.0 °C(Predicted)
• PKA: 9.93±0.70(Predicted)
• PSA: 79.37000
• Density: 1.243±0.06 g/cm3(Predicted)
• LogP: 0.47220
• Storage Temp.: -20°C Freezer, Under inert atmosphere
• Solubility.: Chloroform (Slightly), DMSO, Methanol (Slightly)

Purity/Quality:

99%, ^*data from raw suppliers

HydrazinecarbothioicAcidO-methylEster ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Hydrazinecarbothioic Acid O-methyl Ester acts as a reagent for the synthesis of methidation, an insecticide.

Technology Process of hydrazinecarbothioic acid O-methyl ester

There total 7 articles about hydrazinecarbothioic acid O-methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 40.0%

potassium methylxanthate (2667-20-1) → methyl imidothiocarbamate (19692-07-0)

Guidance literature:

With hydrazine hydrate; In water;

Reference yield:

sodium methyl xanthate (6370-03-2) → methyl imidothiocarbamate (19692-07-0)

Guidance literature:

With hydrazine hydrate;

Reference yield:

methyl O-methyldithiocarbonate (19708-81-7) → methyl imidothiocarbamate (19692-07-0)

Guidance literature:

With hydrazine hydrate; In ethanol;

upstream raw materials:

methyl O-methyldithiocarbonate

2-(methoxycarbonothioylthio)acetic acid

potassium methylxanthate

carbon disulfide

Downstream raw materials:

N'-[1-(4-Chloro-phenyl)-meth-(Z)-ylidene]-hydrazinecarbothioic acid O-methyl ester

N'-[1-(2-Chloro-phenyl)-meth-(Z)-ylidene]-hydrazinecarbothioic acid O-methyl ester

C₉H₁₂N₂O₃S₂

2-amino-5-methoxy-1,3,4-thiadiazole

Refernces

• 1、 Miller, Michael M.,Banville, Jacques,Friends, Todd J.,Gagnon, Mark,Hangeland, Jon J.,Lavallée, Jean-Fran?ois,Martel, Alain,O'Grady, Harold,Rémillard, Roger,Ruediger, Edward,Tremblay, Fran?ois,Posy, Shana L.,Allegretto, Nick J.,Guarino, Victor R.,Harden, David G.,Harper, Timothy W.,Hartl, Karen,Josephs, Jonathan,Malmstrom, Sarah,Watson, Carol,Yang, Yanou,Zhang, Ge,Wong, Pancras,Yang, Jing,Bouvier, Michel,Seiffert, Dietmar A.,Wexler, Ruth R.,Lawrence, R. Michael,Priestley, E. Scott,Marinier, Anne. "Discovery of Potent Protease-Activated Receptor 4 Antagonists with in Vivo Antithrombotic Efficacy". . p. 7400 - 7416. Retrieved 2019/08/26.
• 2、 Dai, Hong,Li, Gang,Chen, Jia,Shi, Yujun,Ge, Shushan,Fan, Chongguang,He, Haibing. "Synthesis and biological activities of novel 1,3,4-thiadiazole-containing pyrazole oxime derivatives". . p. 3818 - 3821. Retrieved 2016/07/21.