Technology Process of Stannane, trimethyl(5-phenyl-2-furanyl)-
There total 2 articles about Stannane, trimethyl(5-phenyl-2-furanyl)- which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
n-butyllithium;
In
diethyl ether; hexane;
at -78°C to soln. of furan (ether) soln. of C4H9Li (C6H14) added,soln. stirred (N2, -78°C, 1 h; 3 h, 20°C), cooled (-78.de gree.C), Sn(CH3)3Cl in ether added dropwise via a siringe, stirred (2 h,-78°C; overnight, room temp.); mixt. quenched with aq. NH4Cl, extd. with ether (twice), ether layers dried (Na2SO4), concd. (vac.), residue distilled;
DOI:10.1039/b005948j
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: potassium carbonate; palladium bis[bis(diphenylphosphino)ferrocene] dichloride / 1,4-dioxane; water / 16 h / 100 °C / Inert atmosphere
2.1: n-butyllithium / hexane; tetrahydrofuran / 2 h / -78 °C
2.2: 1 h / -78 - 20 °C
With
n-butyllithium; palladium bis[bis(diphenylphosphino)ferrocene] dichloride; potassium carbonate;
In
tetrahydrofuran; 1,4-dioxane; hexane; water;
1.1: |Suzuki Coupling;
- Guidance literature:
-
bis(triphenylphosphine)palladium(II)-chloride;
In
tetrahydrofuran;
for 8h;
Heating;
DOI:10.1039/b401579g