Quinoline, decahydro-2-methyl-

Base Information

• Chemical Name: Quinoline, decahydro-2-methyl-
• CAS No.: 20717-43-5
• Molecular Formula: C10H19N
• Molecular Weight: 153.268
• Mol file: 20717-43-5.mol

Synonyms:2-methyl-decahydro-quinoline;2-methyldecahydroquinoline;Decahydrochinaldin;2-Methyl-decahydro-chinolin;decahydro-quinaldine;2-Methyldecahydrochinolin;

Chemical Property of Quinoline, decahydro-2-methyl-

Chemical Property:

• Refractive Index: 1.48
• Boiling Point: 206 °C
• PSA: 12.03000
• LogP: 2.64590

Purity/Quality:

99% ^*data from raw suppliers

2-Methyldecahydroquinoline (mixture of isomers) ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Quinoline, decahydro-2-methyl-

There total 17 articles about Quinoline, decahydro-2-methyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.7%

2-methylquinoline (91-63-4) → decahydro-2-methylquinoline (20717-43-5) + 1,2,3,4-tetrahydro-2-methylquinoline (1780-19-4)

Guidance literature:

With hydrogen; In neat (no solvent); at 80 ℃; for 12h; under 7500.75 Torr; chemoselective reaction; Autoclave;

DOI:10.1039/c6gc02782b

Reference yield: 84.0%

2-methylquinoline (91-63-4) → decahydro-2-methylquinoline (20717-43-5)

Guidance literature:

With hydrogen; In hexane; at 100 ℃; for 3h; under 6000.6 Torr;

DOI:10.1016/j.catcom.2012.11.015

Reference yield:

2-methylquinoline (91-63-4) → decahydro-2-methylquinoline (20717-43-5) + 2-methyl-5,6,7,8-tetrahydroquinoline (2617-98-3) + 1,2,3,4-tetrahydro-2-methylquinoline (1780-19-4)

Guidance literature:

With hydrogen; aluminum oxide; ruthenium; In various solvent(s); at 160 ℃; for 1.6h; under 38786.1 Torr; Product distribution;

upstream raw materials:

2-methylquinoline

2-methyl-5,6,7,8-tetrahydroquinoline

1,2,3,4-tetrahydro-2-methylquinoline

Downstream raw materials:

((2S,4aR,8aR)-2-Methyl-octahydro-quinolin-1-yl)-phenyl-methanone

1,2,3,4-tetrahydro-2-methylquinoline

2-methylquinoline

1,5-diaminoanthraquinone

Refernces

• 1、 Zhang, Sishi,Xu, Jie,Cheng, Hongmei,Zang, Cuicui,Sun, Bin,Jiang, Heyan,Bian, Fengxia. "Highly efficient one-pot multi-directional selective hydrogenation and N-alkylation catalyzed by Ru/LDH under mild conditions". supporting information. . Retrieved 2020/03/30.
• 2、 Jiang, He-Yan,Zheng, Xu-Xu. "Tuning the chemoselective hydrogenation of aromatic ketones, aromatic aldehydes and quinolines catalyzed by phosphine functionalized ionic liquid stabilized ruthenium nanoparticles". . p. 3728 - 3734. Retrieved 2015/07/07.