5-Bromo-2-fluoro-4-nitrotoluene

Base Information

• Chemical Name: 5-Bromo-2-fluoro-4-nitrotoluene
• CAS No.: 208165-95-1
• Molecular Formula: C7H5BrFNO2
• Molecular Weight: 234.02300
• Hs Code.: 2904909090
• Mol file: 208165-95-1.mol

Synonyms:

Chemical Property of 5-Bromo-2-fluoro-4-nitrotoluene

Chemical Property:

• PSA: 45.82000
• LogP: 3.32800

Purity/Quality:

98.5% ^*data from raw suppliers

1-Bromo-4-fluoro-5-methyl-2-nitrobenzene ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 5-Bromo-2-fluoro-4-nitrotoluene

There total 1 articles about 5-Bromo-2-fluoro-4-nitrotoluene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

5-bromo-2-fluorotoluene (51437-00-4) → 5-bromo-2-fluoro-4-nitrotoluene (208165-95-1)

Guidance literature:

5-bromo-2-fluorotoluene; With sulfuric acid; at -5 ℃; for 0.166667h;

With potassium nitrate; at 20 ℃; for 10h;

Reference yield:

5-bromo-2-fluoro-4-nitrotoluene (208165-95-1) + Ethyl 4-bromobutyrate (2969-81-5) → C13H16FNO4

Guidance literature:

With iodine; palladium diacetate; zinc; XPhos; In N,N-dimethyl-formamide; at 0 - 20 ℃; for 15h; Inert atmosphere;

upstream raw materials:

5-bromo-2-fluorotoluene

Refernces

• 1、 -. "Pyridonecarboxylic acid derivatives or salts thereof and drugs containing the same as the active ingredient". . . Retrieved 2008/06/13.