4-[6-(acetyloxy)-3-ethyl-1H-inden-2-yl]phenyl acetate

Base Information

• Chemical Name: 4-[6-(acetyloxy)-3-ethyl-1H-inden-2-yl]phenyl acetate
• CAS No.: 7478-30-0
• Molecular Formula: C₂₁H₂₀O₄
• Molecular Weight: 336.387
• Mol file: 7478-30-0.mol

Synonyms:Inden-6-ol,3-ethyl-2-(p-hydroxyphenyl)-, diacetate (8CI); NSC 402899

Chemical Property of 4-[6-(acetyloxy)-3-ethyl-1H-inden-2-yl]phenyl acetate

Chemical Property:

• Vapor Pressure: 1.91E-08mmHg at 25°C
• Boiling Point: 454.4°C at 760 mmHg
• Flash Point: 225°C
• Density: 1.181g/cm³

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-[6-(acetyloxy)-3-ethyl-1H-inden-2-yl]phenyl acetate

There total 5 articles about 4-[6-(acetyloxy)-3-ethyl-1H-inden-2-yl]phenyl acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-(4-methoxyphenyl)-5-methoxy-1-indanone (7478-21-9) → 6-acetoxy-2-(4-acetoxy-phenyl)-3-ethyl-indene (7478-30-0)

Guidance literature:

Multi-step reaction with 3 steps

1: diethyl ether; benzene / anschliessendes Behandeln mit wss. HCl

2: acetic acid; aqueous HBr

3: sodium acetate

With diethyl ether; hydrogen bromide; sodium acetate; acetic acid; benzene;

DOI:10.1021/ja01252a034

Reference yield:

3-(3-methoxyphenyl)-2-(4-methoxyphenyl)propanoic acid (33902-36-2) → 6-acetoxy-2-(4-acetoxy-phenyl)-3-ethyl-indene (7478-30-0)

Guidance literature:

Multi-step reaction with 4 steps

1: P₂O₅; benzene

2: diethyl ether; benzene / anschliessendes Behandeln mit wss. HCl

3: acetic acid; aqueous HBr

4: sodium acetate

With diethyl ether; hydrogen bromide; sodium acetate; phosphorus pentoxide; acetic acid; benzene;

DOI:10.1021/ja01252a034

Reference yield:

3-ethyl-6-methoxy-2-(4-methoxy-phenyl)-indene (872786-19-1) → 6-acetoxy-2-(4-acetoxy-phenyl)-3-ethyl-indene (7478-30-0)

Guidance literature:

Multi-step reaction with 2 steps

1: acetic acid; aqueous HBr

2: sodium acetate

With hydrogen bromide; sodium acetate; acetic acid;

DOI:10.1021/ja01252a034

upstream raw materials:

3-ethyl-2-(4-hydroxy-phenyl)-inden-6-ol

acetic anhydride

2-(4-methoxyphenyl)-5-methoxy-1-indanone

3-(3-methoxyphenyl)-2-(4-methoxyphenyl)propanoic acid