4-Oxa-6-heptene-2-ol

Base Information

• Chemical Name: 4-Oxa-6-heptene-2-ol
• CAS No.: 21460-36-6
• Molecular Formula: C6H12O2
• Molecular Weight: 116.16
• Hs Code.: 2909499000
• Mol file: 21460-36-6.mol

Synonyms:allyloxypropan-2-ol;Propylene glycol 1-allyl ether;allyl 2-hydroxypropyl ether;UNII-QRB8092KPK;1-allyloxy-propan-2-ol;2-allyloxy-1-methylethanol;

Chemical Property of 4-Oxa-6-heptene-2-ol

Chemical Property:

• Vapor Pressure: 0.59mmHg at 25°C
• Boiling Point: 166.5oC at 760 mmHg
• PKA: 14.57±0.20(Predicted)
• Flash Point: 57.3oC
• PSA: 29.46000
• Density: 0.915g/cm3
• LogP: 0.56980

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Use Description: 4-Oxa-6-heptene-2-ol, a chemical compound, finds applications in various fields. In the field of organic synthesis and pharmaceuticals, it serves as a versatile intermediate for the production of pharmaceutical drugs and fine chemicals, potentially contributing to the development of medications with therapeutic applications. In the realm of materials science and polymer chemistry, this compound can be used as a monomer or building block for the creation of specialized polymers or coatings, with potential applications in adhesives, plastics, and surface treatments. Additionally, in the fragrance and flavor industry, it may be employed as an aroma compound or flavoring agent, contributing to the sensory profiles of various products like perfumes, cosmetics, and food items. Its multifaceted roles as a pharmaceutical intermediate, materials precursor, and flavoring agent underscore its significance in advancing pharmaceuticals, materials science, and sensory experiences in different fields.

Technology Process of 4-Oxa-6-heptene-2-ol

There total 2 articles about 4-Oxa-6-heptene-2-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-allyloxypropan-2-one (53135-67-4) + diphenylsilane (775-12-2) → 2-allyloxy-1-methylethanol (21460-36-6) + (3,4-Dimethyl-tetrahydro-furan-3-yloxy)-diphenyl-silane

Guidance literature:

With bis(cyclopentadienyl)bis(trimethylphosphane)titanium(II); trimethylphosphane; In toluene; at -20 ℃; Yield given. Yields of byproduct given;

DOI:10.1021/ja00130a021

Reference yield:

1-allyloxypropan-2-one (53135-67-4) → 2-allyloxy-1-methylethanol (21460-36-6) + (3,4-Dimethyl-tetrahydro-furan-3-yloxy)-diphenyl-silane

Guidance literature:

With bis(cyclopentadienyl)bis(trimethylphosphane)titanium(II); diphenylsilane; trimethylphosphane; Yield given. Multistep reaction. Yields of byproduct given; 1.) toluene, -20 deg C;

DOI:10.1021/ja00130a021

Reference yield: 85.0%

2-allyloxy-1-methylethanol (21460-36-6) + benzaldehyde (100-52-7) → 1-Phenyl-3-buten-1-ol (80735-94-0,936-58-3)

Guidance literature:

With tin(ll) chloride; bis(1,5-cyclooctadiene)diiridium(I) dichloride; In tetrahydrofuran; water; at 50 ℃; for 46h;

DOI:10.1016/j.tetlet.2007.06.117

upstream raw materials:

1-allyloxypropan-2-one

diphenylsilane

Downstream raw materials:

1-phenylhex-5-en-3-ol

1-Phenyl-3-buten-1-ol

1-(4-chlorophenyl)but-3-en-1-ol

1-phenylhex-1,5-dien-3-ol

Refernces