5-Chloro-2-hydroxy-3-iodobenzaldehyde

Base Information

• Chemical Name: 5-Chloro-2-hydroxy-3-iodobenzaldehyde
• CAS No.: 215124-03-1
• Molecular Formula: C7H4ClIO2
• Molecular Weight: 282.465
• Hs Code.: 2913000090
• European Community (EC) Number: 803-075-5
• DSSTox Substance ID: DTXSID00396213
• Nikkaji Number: J2.913.219D
• Wikidata: Q82196804
• Mol file: 215124-03-1.mol

Synonyms:5-chloro-2-hydroxy-3-iodobenzaldehyde;215124-03-1;3-iodo-5-chlorosalicylaldehyde;5-Chloro-3-iodosalicylaldehyde;SCHEMBL3207260;DTXSID00396213;AKOS B028995;QNSRWUDUYCZRQJ-UHFFFAOYSA-N;MFCD00462964;STK400287;AKOS000113693;2-Hydroxy-3-iodo-5-chlorobenzaldehyde;SB85360;BS-53054;CS-0118165;5-Chloro-2-hydroxy-3-iodobenzaldehyde, 97%;E85519

Chemical Property of 5-Chloro-2-hydroxy-3-iodobenzaldehyde

Chemical Property:

• Vapor Pressure: 0.0179mmHg at 25°C
• Melting Point: 87-92°C
• Boiling Point: 245.9oC at 760 mmHg
• Flash Point: 102.5oC
• PSA: 37.30000
• Density: 2.114g/cm3
• LogP: 2.46270
• XLogP3: 2.9
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• Exact Mass: 281.89445
• Heavy Atom Count: 11
• Complexity: 153

Purity/Quality:

98%,99%, ^*data from raw suppliers

5-Chloro-2-hydroxy-3-iodobenzaldehyde 97% ^*data from reagent suppliers

Safty Information:

• Hazard Codes: T
• Statements: 25-36
• Safety Statements: 26-45

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=C(C=C(C(=C1C=O)O)I)Cl

Technology Process of 5-Chloro-2-hydroxy-3-iodobenzaldehyde

There total 3 articles about 5-Chloro-2-hydroxy-3-iodobenzaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

→ 5-chloro-3-iodosalicylaldehyde (215124-03-1)

Guidance literature:

Reference yield: 94.0%

5-chlorosalicyclaldehyde (635-93-8) → 5-chloro-3-iodosalicylaldehyde (215124-03-1)

Guidance literature:

With N-iodo-succinimide; In acetic acid; at 95 ℃; for 3h;

Reference yield:

4-chloro-2-iodo phenol (71643-66-8) → 5-chloro-3-iodosalicylaldehyde (215124-03-1)

Guidance literature:

upstream raw materials:

5-chlorosalicyclaldehyde

4-chloro-2-iodo phenol

Refernces

• 1、 -. "FUSED 9-MEMBERED RING DERIVATIVES HAVING AUTOTAXIN INHIBITORY ACTIVITY". Paragraph 0123. . Retrieved 2017/01/02.
• 2、 Shinde, Avinash T.,Zangade, Sainath B.,Chavan, Shivaji B.,Vibhute, Archana Y.,Nalwar, Yogesh S.,Vibhute, Yeshwant B.. "A practical iodination of aromatic compounds by using iodine and iodic acid". experimental part. p. 3506 - 3513. Retrieved 2011/02/22.