2-hydroxy-11H-benzo[a]carbazole-3-carboxylic acid

Base Information

• Chemical Name: 2-hydroxy-11H-benzo[a]carbazole-3-carboxylic acid
• CAS No.: 84-43-5
• Molecular Formula: C17H11 N O3
• Molecular Weight: 277.279
• Hs Code.: 2933990090
• European Community (EC) Number: 201-529-1
• NSC Number: 58411
• UNII: 76KBX76TT4
• DSSTox Substance ID: DTXSID80232887
• Nikkaji Number: J192.616K
• Wikidata: Q83114078
• ChEMBL ID: CHEMBL490409
• Mol file: 84-43-5.mol

Synonyms:84-43-5;2-hydroxy-11H-benzo[a]carbazole-3-carboxylic acid;2-Hydroxy-11H-benzo(a)carbazole-3-carboxylic acid;CHEMBL490409;EINECS 201-529-1;NSC-58411;11H-Benzo[a]carbazole-3-carboxylic acid, 2-hydroxy-;11H-Benzo(a)carbazole-3-carboxylic acid, 2-hydroxy-;2-Hydroxybenzocarbazole-3-carboxylic acid;NSC58411;Pink 3B Tolylamide;Oprea1_341246;76KBX76TT4;SCHEMBL1247817;C17H11NO3;DTXSID80232887;BDBM50263906;NSC 58411;2-Hydroxy-3-carboxybenzo[a]carbazole;2-hydroxy-11H-benzo[a]carbazol-3-carboxylsyre;2-Hydrazinyl-4,6-dimethyl-5-nitronicotinonitrile;A840781

Chemical Property of 2-hydroxy-11H-benzo[a]carbazole-3-carboxylic acid

Chemical Property:

• Vapor Pressure: 3.1E-14mmHg at 25°C
• Boiling Point: 578.7°C at 760 mmHg
• Flash Point: 303.8°C
• PSA: 73.32000
• Density: 1.531g/cm³
• LogP: 3.87810
• XLogP3: 4.4
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 1
• Exact Mass: 277.07389321
• Heavy Atom Count: 21
• Complexity: 426

Purity/Quality:

99%, ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C2C(=C1)C3=C(N2)C4=CC(=C(C=C4C=C3)C(=O)O)O

Technology Process of 2-hydroxy-11H-benzo[a]carbazole-3-carboxylic acid

There total 3 articles about 2-hydroxy-11H-benzo[a]carbazole-3-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-hydroxybenzo[a]carbazole (848771-87-9) → 2-hydroxy-11H-benzo(a)carbazole-3-carboxylic acid (84-43-5)

Guidance literature:

With potassium hydroxide; carbon dioxide; at 220 ℃; under 29420.3 Torr;

Reference yield:

3,5-dihydroxy-2-naphthoic acid (89-35-0) → 2-hydroxy-11H-benzo(a)carbazole-3-carboxylic acid (84-43-5)

Guidance literature:

With sodium hydroxide; sodium hydrogensulfite; anschliessendes Erhitzen mit Phenylhydrazin und H₂SO₄;

Reference yield:

1-methyl-4-nitrosobenzene (623-11-0) + 3,5-dihydroxy-2-naphthoic acid (89-35-0) → 2-hydroxy-11H-benzo(a)carbazole-3-carboxylic acid (84-43-5)

Guidance literature:

anschliessendes Erhitzen mit Phenylhydrazin und wss. Schwefelsaeure;

upstream raw materials:

2-hydroxybenzo[a]carbazole

3,5-dihydroxy-2-naphthoic acid

1-methyl-4-nitrosobenzene

Downstream raw materials:

1-(4-Diethylamino-phenylazo)-2-hydroxy-11H-benzo[a]carbazole-3-carboxylic acid