1-ETHOXY-4-CHLOROPHTHALAZINE

Base Information

• Chemical Name: 1-ETHOXY-4-CHLOROPHTHALAZINE
• CAS No.: 22378-29-6
• Molecular Formula: C10H9ClN2O
• Molecular Weight: 208.647
• Hs Code.: 2933990090
• Mol file: 22378-29-6.mol

Synonyms:4-Chlor-1-ethoxy-phthalazin;1-Aethoxy-4-chlor-phthalazin;1-chloro-4-ethoxy-phthalazine;1-ethoxy-4-chloro-phthalazine;

Chemical Property of 1-ETHOXY-4-CHLOROPHTHALAZINE

Chemical Property:

• Vapor Pressure: 2.48E-06mmHg at 25°C
• Boiling Point: 402.8oC at 760 mmHg
• Flash Point: 197.4oC
• PSA: 35.01000
• Density: 1.284g/cm3
• LogP: 2.68190

Purity/Quality:

99% ^*data from raw suppliers

1-chloro-4-ethoxyphthalazine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-ETHOXY-4-CHLOROPHTHALAZINE

There total 5 articles about 1-ETHOXY-4-CHLOROPHTHALAZINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

1,4-dichlorophthalazine (4752-10-7) + sodium ethanolate (141-52-6) → 1-chloro-4-ethoxyphthalazine (22378-29-6)

Guidance literature:

With sodium; In ethanol; for 0.5h; Heating;

DOI:10.1023/A:1013979709884

Reference yield:

1,4-dichlorophthalazine (4752-10-7) → 3-methoxy-4,5-dimethyl-6-chloropyridazine + 1-chloro-4-ethoxyphthalazine (22378-29-6)

Guidance literature:

In ethanol;

Reference yield:

1,4-dichlorophthalazine (4752-10-7) → 1-chloro-4-ethoxyphthalazine (22378-29-6)

Guidance literature:

In ethanol; hexane;

upstream raw materials:

1,4-dichlorophthalazine

sodium ethanolate

ethanol

Downstream raw materials:

1,4-bis(hydrazino)phthalazine

Refernces

• 1、 -. "Hepatitis C Virus Inhibitors". Page/Page column. . Retrieved 2013/05/21.
• 2、 Yanilkin,Buzykin,Morozov,Nastapova,Maksimyuk,Eliseenkova. "Electrochemical reduction of 1,4-disubstituted phthalazines". . p. 1636 - 1646. Retrieved 2007/10/03.