Methanone, bis(3-amino-4-hydroxyphenyl)-

Base Information

• Chemical Name: Methanone, bis(3-amino-4-hydroxyphenyl)-
• CAS No.: 22445-98-3
• Molecular Formula: C13H12N2O3
• Molecular Weight: 244.25
• Mol file: 22445-98-3.mol

Synonyms:di3-amino-4-hydroxyphenyl ketone;

Chemical Property of Methanone, bis(3-amino-4-hydroxyphenyl)-

Chemical Property:

• PSA: 109.57000
• LogP: 2.65560

Purity/Quality:

99% ^*data from raw suppliers

Bis(3-amino-4-hydroxyphenyl)methanone ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Methanone, bis(3-amino-4-hydroxyphenyl)-

There total 5 articles about Methanone, bis(3-amino-4-hydroxyphenyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.12%

3,3'-dinitro-4,4'-dihydroxybenzophenone (37567-35-4) → 4,4'-dihydroxy-3,3'-diaminobenzophenone (22445-98-3)

Guidance literature:

With palladium 10% on activated carbon; hydrazine hydrate; In water; at 75 ℃; for 6h; Reagent/catalyst; Temperature; Inert atmosphere;

Reference yield:

4-chloro-benzoyl chloride (122-01-0) → 4,4'-dihydroxy-3,3'-diaminobenzophenone (22445-98-3)

Guidance literature:

Multi-step reaction with 4 steps

1: aluminum (III) chloride / 8 h / 50 - 150 °C

2: sulfuric acid; nitric acid / 30 - 70 °C

3: sodium hydroxide / ethanol; water / 24 h / 75 °C

4: palladium 10% on activated carbon; hydrazine hydrate / water / 6 h / 75 °C / Inert atmosphere

With aluminum (III) chloride; sulfuric acid; palladium 10% on activated carbon; nitric acid; hydrazine hydrate; sodium hydroxide; In ethanol; water;

Reference yield:

4,4'-Dichlorobenzophenone (90-98-2) → 4,4'-dihydroxy-3,3'-diaminobenzophenone (22445-98-3)

Guidance literature:

Multi-step reaction with 3 steps

1: sulfuric acid; nitric acid / 30 - 70 °C

2: sodium hydroxide / ethanol; water / 24 h / 75 °C

3: palladium 10% on activated carbon; hydrazine hydrate / water / 6 h / 75 °C / Inert atmosphere

With sulfuric acid; palladium 10% on activated carbon; nitric acid; hydrazine hydrate; sodium hydroxide; In ethanol; water;

upstream raw materials:

chlorobenzene

4-chloro-benzoyl chloride

4,4'-Dichlorobenzophenone

3,3'-dinitro-4,4'-dihydroxybenzophenone

Refernces