Deltasol

Base Information

• Chemical Name: Deltasol
• CAS No.: 3800-86-0
• Deprecated CAS: 318480-27-2
• Molecular Formula: C₂₆H₃₃FO₈
• Molecular Weight: 492.542
• NSC Number: 37630
• UNII: 9UY5TBO121
• DSSTox Substance ID: DTXSID90191416
• Nikkaji Number: J548.231C
• Wikidata: Q27273259
• Mol file: 3800-86-0.mol

Synonyms:Deltasol;Dexamethasone hemisuccinate;3800-86-0;dexamethasone succinate;Dexamethasone 21-hemisuccinate;UNII-9UY5TBO121;9UY5TBO121;NSC 37630;NSC-37630;(11beta,16alpha)-21-(3-Carboxy-1-oxopropoxy)-9-fluoro-11,17-dihydroxy-16-methylpregna-1,4-diene-3,20-dione;4-[2-[(8S,9R,10S,11S,13S,14S,16R,17R)-9-fluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethoxy]-4-oxobutanoic acid;Pregna-1,4-diene-3,20-dione, 21-(3-carboxy-1-oxopropoxy)-9-fluoro-11,17-dihydroxy-16-methyl-, (11beta,16alpha)-;C26-H33-F-O8;NSC37630;SCHEMBL17170544;DTXSID90191416;Q27273259;PREGNA-1,4-DIENE-3,20-DIONE, 21-(3-CARBOXY-1-OXOPROPOXY)-9-FLUORO-11,17-DIHYDROXY-16-METHYL-, (11.BETA.,16.ALPHA.)-;PREGNA-1,4-DIENE-3,20-DIONE, 9-FLUORO-11.BETA.,17,21-TRIHYDROXY-16.ALPHA.-METHYL-, 21-(HYDROGEN SUCCINATE)

Chemical Property of Deltasol

Chemical Property:

• Vapor Pressure: 8.72E-22mmHg at 25°C
• Melting Point: >170°C (subl.)
• Boiling Point: 686 ºC at 760 mmHg
• Flash Point: 368.7 ºC
• PSA: 138.20000
• Density: 1.36 g/cm³
• LogP: 2.31140
• Storage Temp.: Refrigerator
• Solubility.: DMSO (Slightly), Methanol (Slightly), Pyridine (Slightly)
• XLogP3: 2
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 9
• Rotatable Bond Count: 7
• Exact Mass: 492.21594617
• Heavy Atom Count: 35
• Complexity: 1030

Purity/Quality:

99%, ^*data from raw suppliers

DexamethasoneHemisuccinate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1CC2C3CCC4=CC(=O)C=CC4(C3(C(CC2(C1(C(=O)COC(=O)CCC(=O)O)O)C)O)F)C
• Isomeric SMILES: C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@@]4([C@]3([C@H](C[C@@]2([C@]1(C(=O)COC(=O)CCC(=O)O)O)C)O)F)C
• Uses: Dexamethasone Hemisuccinate is a derivative of Dexamethasone (D298800); a glucocorticoid used as an anti-inflammatory agent. It regulates T cell survival, growth, and differentiation. Dexamethasone also inhibits the induction of nitric oxide synthase.

Technology Process of Deltasol

There total 1 articles about Deltasol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ Succinic acid mono-[2-((9R,10S,11S,13S,17R)-9-fluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl)-2-oxo-ethyl] ester (3800-86-0,27297-42-3)

Guidance literature:

Entspr. Alkohol, Bernsteinsaeureanhydrid;