benzyl 3-phenylpropanoate

Base Information

• Chemical Name: benzyl 3-phenylpropanoate
• CAS No.: 22767-96-0
• Molecular Formula: C16H16O2
• Molecular Weight: 240.302
• Mol file: 22767-96-0.mol

Synonyms:3-Phenyl-propionic acid benzyl ester;benzyl 3-phenylpropionate;phenylmethyl 3-phenylpropionate;benzyl 3‐phenylpropanoate;3-phenylpropionic acid benzyl ester;Benzenepropanoic acid, phenylmethyl ester;hydrocinnamic acid benzyl ester;benzyl dihydrocinnamate;

Chemical Property of benzyl 3-phenylpropanoate

Chemical Property:

• Vapor Pressure: 4.04E-05mmHg at 25°C
• Refractive Index: 1.6290 (estimate)
• Boiling Point: 198 - 199 °C (20 mmHg)
• PSA: 26.30000
• Density: 1.0900
• LogP: 3.36260

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of benzyl 3-phenylpropanoate

There total 118 articles about benzyl 3-phenylpropanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

ethyl dihydrocinnamate (2021-28-5) + benzyl alcohol (100-51-6,185532-71-2) → ethanol (64-17-5) + Benzyl 3-phenylpropionate (22767-96-0)

Guidance literature:

2[{Cl(C₆F₁₃CH₂CH₂)2SnOSn(CH₂CH₂C₆F₁₃)2Cl}2]; In various solvent(s); at 150 ℃; for 16h;

DOI:10.1002/1521-3773(20011001)40:19<3670::AID-ANIE3670>3.0.CO;2-9

Reference yield: 82.0%

1,3-dioxoisoindolin-2-yl 3-phenylpropanoate (84379-71-5) + benzyl alcohol (100-51-6,185532-71-2) → Benzyl 3-phenylpropionate (22767-96-0) + benzyl anthranilate (82185-41-9)

Guidance literature:

With dmap; In dichloromethane; at 20 ℃; for 24h; Inert atmosphere;

DOI:10.3987/COM-09-11643

Reference yield: 71.0%

(carbobenzyloxymethylene)triphenylphosphorane (15097-38-8) + benzyl alcohol (100-51-6,185532-71-2) → (E)-cinnamic acid benzyl ester (103-41-3,8014-16-2) + Benzyl 3-phenylpropionate (22767-96-0) + benzaldehyde (100-52-7)

Guidance literature:

With bis(1,5-cyclooctadiene)diiridium(I) dichloride; 1,3-bis-(diphenylphosphino)propane; caesium carbonate; In toluene; at 150 ℃; for 72h;

DOI:10.1002/anie.200290034

upstream raw materials:

(E)-cinnamic acid benzyl ester

N-methyl-N-phenyl-benzenemethanamine

3-Phenylpropionic acid

benzyl alcohol

Downstream raw materials:

1-octyl 3-phenylpropanoate

ethyl dihydrocinnamate

allyl 3-phenylpropionate

Refernces

• 1、 Chen, Jinhua,Chu, Jianxiao,Huang, Minyan,Ren, Wenlong,Shi, Yian. "Pd-Catalyzed Regioselective Hydroesterification of Olefins with 2,2,2-Trifluoroethyl Formate". . . Retrieved 2020.
• 2、 Liu, Xin,Werner, Thomas. "Selective Construction of C?C and C=C Bonds by Manganese Catalyzed Coupling of Alcohols with Phosphorus Ylides". supporting information. p. 1096 - 1104. Retrieved 2020/12/31.
• 3、 Lee, Hyo-Jun,Huang, Xiao,Sakaki, Shigeyoshi,Maruoka, Keiji. "Metal-free approach for hindered amide-bond formation with hypervalent iodine(iii) reagents: application to hindered peptide synthesis". supporting information. p. 848 - 855. Retrieved 2021/02/09.