N-Phenyl-2,3,4,5,6-pentafluorobenzenemethanimine

Base Information

• Chemical Name: N-Phenyl-2,3,4,5,6-pentafluorobenzenemethanimine
• CAS No.: 2341-86-8
• Molecular Formula: C13H6F5N
• Molecular Weight: 271.189
• Hs Code.: 2921420090
• Mol file: 2341-86-8.mol

Synonyms:N-phenyl pentafluorophenyl aldimine;perfluorobenzylidenebenzenamine;N-pentafluorobenziliden aniline;2,3,4,5,6-pentafluorobenzylidene aniline;

Chemical Property of N-Phenyl-2,3,4,5,6-pentafluorobenzenemethanimine

Chemical Property:

• PSA: 12.36000
• LogP: 4.13270

Purity/Quality:

95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of N-Phenyl-2,3,4,5,6-pentafluorobenzenemethanimine

There total 6 articles about N-Phenyl-2,3,4,5,6-pentafluorobenzenemethanimine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

perfluorobenzaldehyde (653-37-2) + aniline (62-53-3) → 1-(perfluorophenyl)-N-phenylmethanimine (2341-86-8)

Guidance literature:

In dichloromethane; for 1h; Ambient temperature;

Reference yield: 48.0%

perfluorobenzaldehyde (653-37-2) + aniline (62-53-3) → 1,2,3,4-tetrafluoro-acridine (14186-61-9) + 1-(perfluorophenyl)-N-phenylmethanimine (2341-86-8) + 3-anilino-1,2,4-trifluoroacridine + Phenyl-{2,3,5,6-tetrafluoro-4-[(E)-phenyliminomethyl]-phenyl}-amine

Guidance literature:

In 1,2-dichloro-benzene; at 180 ℃; for 68h;

Reference yield: 20.0%

perfluorobenzaldehyde (653-37-2) + propargyl alcohol (107-19-7) + aniline (62-53-3) → 1-(perfluorophenyl)-N-phenylmethanimine (2341-86-8) + 4-hydroxymethyl-2-pentafluorophenyl-quinoline

Guidance literature:

With montmorillonite clay; copper(I) bromide; microwave irradiation;

DOI:10.1016/j.tetlet.2004.04.179

upstream raw materials:

perfluorobenzaldehyde

aniline

propargyl alcohol

bromopentafluorobenzene

Downstream raw materials:

N-<3,4,5-Trifluor-2,6-diphenyl-benzyliden>-anilin

(ortho-F₄C₆-CHN-C₆H₅)Co(II)(F)(PMe₃)₂

N-[(3,4,5-trifluoro-2,6-dimethylphenyl)methylene]aniline

N-[(3,4,5,6-tetrafluoro-2-methylphenyl)methylene]aniline

Refernces

• 1、 Ye, Jian-Heng,Bellotti, Peter,Paulisch, Tiffany O.,Daniliuc, Constantin G.,Glorius, Frank. "Visible-Light-Induced Cycloaddition of α-Ketoacylsilanes with Imines: Facile Access to β-Lactams". supporting information. p. 13671 - 13676. Retrieved 2021/05/11.
• 2、 Paw?owska, Agata,Volle, Jean-No?l,Virieux, David,Pirat, Jean-Luc,Janiak, Agnieszka,Nowicki, Mateusz,Hoffmann, Marcin,Pluskota-Karwatka, Donata. "Perfluorophenyl phosphonate analogues of aromatic amino acids: Synthesis, X-ray and DFT studies". . p. 975 - 986. Retrieved 2018/01/27.