Methane, chloro(methylsulfonyl)-

Base Information

• Chemical Name: Methane, chloro(methylsulfonyl)-
• CAS No.: 2351-74-8
• Molecular Formula: C2H5ClO2S
• Molecular Weight: 128.579
• Hs Code.: 2904909090
• European Community (EC) Number: 819-300-5
• DSSTox Substance ID: DTXSID40464985
• Nikkaji Number: J1.864.783D
• Wikidata: Q82290596
• Mol file: 2351-74-8.mol

Synonyms:2351-74-8;chloro(methanesulfonyl)methane;Methane, chloro(methylsulfonyl)-;chloro(methylsulfonyl)methane;Chloromethylsulfonylmethane;chloromethyl methyl sulfone;MFCD19231985;SCHEMBL515550;DTXSID40464985;MZMGJAFJUYKKLI-UHFFFAOYSA-N;CAA35174;AKOS005206976;BS-12674;SY197808;EN300-99261

Chemical Property of Methane, chloro(methylsulfonyl)-

Chemical Property:

• Melting Point: 33-34 °C
• Boiling Point: 134 °C(Press: 17 Torr)
• PSA: 42.52000
• Density: 1.368±0.06 g/cm3(Predicted)
• LogP: 1.30810
• XLogP3: 0.3
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• Exact Mass: 127.9698783
• Heavy Atom Count: 6
• Complexity: 108

Purity/Quality:

95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CS(=O)(=O)CCl
• Uses: Chloromethyl Methyl Sulfone is used in the electroplating bath containing stannous salt.

Technology Process of Methane, chloro(methylsulfonyl)-

There total 2 articles about Methane, chloro(methylsulfonyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

2-chloro-2-(methanesulfonyl)-1-phenylethanone (25093-89-4) → chloromethylsulfonylmethane (2351-74-8) + benzoic acid (65-85-0,8013-63-6)

Guidance literature:

With sodium hydroxide; In water; for 2h; Ambient temperature;

Reference yield:

2-chloro-2-(methanesulfonyl)-1-phenylethanone (25093-89-4) → chloromethylsulfonylmethane (2351-74-8) + benzoic acid ethyl ester (93-89-0,99341-95-4)

Guidance literature:

With potassium cyanide; In ethanol; for 4h; Product distribution; Ambient temperature; other nucleophiles, reaction times, other solvent;

Reference yield: 96.0%

chloromethylsulfonylmethane (2351-74-8) + benzaldehyde (100-52-7) → (2R,3R)-2-Methanesulfonyl-3-phenyl-oxirane

Guidance literature:

chloromethylsulfonylmethane; benzaldehyde; With potassium tert-butylate; In tetrahydrofuran; at -78 ℃; for 0.5h;

In tetrahydrofuran; at -78 - 0 ℃;

DOI:10.1016/S0040-4039(02)02825-3

upstream raw materials:

2-chloro-2-(methanesulfonyl)-1-phenylethanone

Downstream raw materials:

methyl((methylsulfonyl)methyl)sulfane

C₁₅H₁₆O₂S₂

C₂₁H₂₀O₂S₂

Methanesulfonylmethylsulfanyl-benzene

Refernces

• 1、 Grosset, Stuart J.,Dubey, Pramod K.,Gill, Glen H.,Cameron, Stanley T.,Gardner, Patrick A.. "THE PREPARATION, SPECTRAL PROPERTIES, STRUCTURES, AND BASE-INDUCED CLEAVAGE REACTIONS OF SOME α-HALO-β-KETOSULFONES". . p. 798 - 807. Retrieved 2007/10/02.