Technology Process of Phenol, 2,2'-(1,2-ethanediyl)bis[6-methyl-
There total 4 articles about Phenol, 2,2'-(1,2-ethanediyl)bis[6-methyl- which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
C18H22O4;
With
tert.-butyl lithium;
In
diethyl ether;
at 0 - 25 ℃;
methyl iodide;
In
diethyl ether;
at 0 - 25 ℃;
With
hydrogenchloride;
In
diethyl ether; ethanol;
DOI:10.1016/j.jorganchem.2003.08.046
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: 94 percent / H2 / Pd/C / tetrahydrofuran / 20 °C
2.1: 78 percent / NaH / tetrahydrofuran / 25 °C
3.1: tert-BuLi / diethyl ether / 0 - 25 °C
3.2: diethyl ether / 0 - 25 °C
3.3: 95 percent / HCl / ethanol; diethyl ether
With
hydrogen; tert.-butyl lithium; sodium hydride;
palladium on activated charcoal;
In
tetrahydrofuran; diethyl ether;
DOI:10.1016/j.jorganchem.2003.08.046
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: 48 percent / TiCl4; Zn / dioxane / 100 °C
2.1: 94 percent / H2 / Pd/C / tetrahydrofuran / 20 °C
3.1: 78 percent / NaH / tetrahydrofuran / 25 °C
4.1: tert-BuLi / diethyl ether / 0 - 25 °C
4.2: diethyl ether / 0 - 25 °C
4.3: 95 percent / HCl / ethanol; diethyl ether
With
hydrogen; tert.-butyl lithium; titanium tetrachloride; sodium hydride; zinc;
palladium on activated charcoal;
In
tetrahydrofuran; 1,4-dioxane; diethyl ether;
1.1: McMurry coupling;
DOI:10.1016/j.jorganchem.2003.08.046