2-Methoxycyclohex-2-enone

Base Information

• Chemical Name: 2-Methoxycyclohex-2-enone
• CAS No.: 23740-37-6
• Molecular Formula: C7H10O2
• Molecular Weight: 126.155
• Hs Code.: 2914509090
• DSSTox Substance ID: DTXSID20500395
• Nikkaji Number: J609.354J
• Wikidata: Q82351951
• Mol file: 23740-37-6.mol

Synonyms:2-Methoxycyclohex-2-enone;23740-37-6;2-methoxy-2-cyclohexen-1-one;2-METHOXY-CYCLOHEX-2-ENONE;2-methoxycyclohex-2-en-1-one;SCHEMBL1804084;DTXSID20500395;YAA74037;MFCD00154233;AKOS024262167;SB35859;AS-47363;CS-0340779;EN300-382764;F13444

Chemical Property of 2-Methoxycyclohex-2-enone

Chemical Property:

• Boiling Point: 100-117 °C(Press: 20 Torr)
• PSA: 26.30000
• Density: 1.03±0.1 g/cm3(Predicted)
• LogP: 1.26970
• XLogP3: 1.1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• Exact Mass: 126.068079557
• Heavy Atom Count: 9
• Complexity: 147

Purity/Quality:

99% ^*data from raw suppliers

2-Methoxy-2-cyclohexen-1-one ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=CCCCC1=O

Technology Process of 2-Methoxycyclohex-2-enone

There total 21 articles about 2-Methoxycyclohex-2-enone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

7-oxabicyclo[4.1.0]heptan-2-one (6705-49-3) + methanol (67-56-1) → 2-methoxycyclohex-2-en-1-one (23740-37-6)

Guidance literature:

With sulfuric acid; at 20 ℃; for 0.5h;

Reference yield: 93.0%

7-oxabicyclo[4.1.0]heptan-2-one (6705-49-3) → 2-hydroxy-2-cyclohexen-1-one (10316-66-2) + 2-methoxycyclohex-2-en-1-one (23740-37-6)

Guidance literature:

With sulfuric acid; at 20 ℃; for 21h;

Reference yield: 88.0%

Trimethylmethoxysilane (1825-61-2) + 2-hydroxy-2-cyclohexen-1-one (10316-66-2) → 2-methoxycyclohex-2-en-1-one (23740-37-6)

Guidance literature:

With trifluorormethanesulfonic acid; In dichloromethane; Ambient temperature;

DOI:10.1016/S0040-4039(00)85105-9

upstream raw materials:

7-oxabicyclo[4.1.0]heptan-2-one

methanol

chlorhydrate de dimethylammonio-2 cyclohexene-2 one

Trimethylmethoxysilane

Downstream raw materials:

(3S,4R)-3-[(R)-1-(tert-Butyl-dimethyl-silanyloxy)-ethyl]-4-((S)-3-methoxy-2-oxo-cyclohex-3-enyl)-azetidin-2-one

(3S,4R)-3-[(R)-1-(tert-Butyl-dimethyl-silanyloxy)-ethyl]-4-((R)-3-methoxy-2-oxo-cyclohex-3-enyl)-azetidin-2-one

1-((E)-Hepta-4,6-dienyl)-2-methoxy-cyclohex-2-enol

3-bromo-2-methoxycyclohex-2-en-1-one

Refernces

• 1、 Schank, Kurt,Beck, Horst,Pistorius, Susanne. "Ozonolysis of enol ethers. Part 10. Ozonization of enol ethers from 1,2- and 1,3-dicarbonyl compounds: Direct quantitative synthesis of phthalonic acid anhydride". . p. 2025 - 2049. Retrieved 2007/10/03.
• 2、 He, Liangyou,Horiuchi, C. Akira. "Oxidation of 2-substituted cycloalkanones with cerium(IV) sulfate tetrahydrate in alcohols and acetic acid". . p. 2515 - 2521. Retrieved 2007/10/03.