1,3-Isobenzofurandione, 4,5,6,7-tetrahydro-4-methyl-

Base Information

• Chemical Name: 1,3-Isobenzofurandione, 4,5,6,7-tetrahydro-4-methyl-
• CAS No.: 23939-61-9
• Molecular Formula: C9H10O3
• Molecular Weight: 166.177
• Mol file: 23939-61-9.mol

Synonyms:3-Methyl-1,4-cyclohexadien-1,2-dicarbonsaeureanhydrid(?);3-methyl-1-cyclohexene-1,2-dicarboxylic anhydride;3-methyl-3,4,5,6-tetrahydrophthalic acid anhydride;3-methyl-cyclohex-1-ene-1,2-dicarboxylic acid anhydride;4-Methyl-4,5,6,7-tetrahydro-isobenzofuran-1,3-dione;3-Methyl-tetrahydro-phthalsaeureanhydrid;

Chemical Property of 1,3-Isobenzofurandione, 4,5,6,7-tetrahydro-4-methyl-

Chemical Property:

• Boiling Point: 156 - 158 °C (6 mmHg)
• PSA: 43.37000
• LogP: 1.18640

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1,3-Isobenzofurandione, 4,5,6,7-tetrahydro-4-methyl-

There total 15 articles about 1,3-Isobenzofurandione, 4,5,6,7-tetrahydro-4-methyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

1-methyl-7-oxa-bicyclo[2.2.1]heptane-2,3-dicarboxylic acid anhydride (6345-56-8) → 3-methylphthalic acid anhydride (4792-30-7) + 3-methylcyclohexene-1,2-dicarboxylic acid anhydride (23939-61-9)

Guidance literature:

With zeolite Y catalyst that contained 1%wt Pd (“Pd/H-Y”); at 200 ℃; Reagent/catalyst; Inert atmosphere;

Reference yield:

C9H10O4 → 3-methylphthalic acid anhydride (4792-30-7) + 3-methylcyclohexene-1,2-dicarboxylic acid anhydride (23939-61-9) + m-Toluic acid (99-04-7)

Guidance literature:

With 3 wtpercent Pd/C loaded on zeolite H-Y with a silica-alumina ratio of 40; In toluene; at 200 ℃; for 4h; under 750.075 Torr; Reagent/catalyst; Inert atmosphere;

DOI:10.1002/cssc.201600776

Reference yield:

C9H10O4 → ortho-methylbenzoic acid (118-90-1) + 3-methylphthalic acid anhydride (4792-30-7) + 3-methylcyclohexene-1,2-dicarboxylic acid anhydride (23939-61-9) + C9H10O4 + m-Toluic acid (99-04-7)

Guidance literature:

With zeolite H-Y with a silica-alumina ratio of 2.6; In toluene; at 200 ℃; for 4h; under 750.075 Torr; Inert atmosphere;

DOI:10.1002/cssc.201600776

upstream raw materials:

1-methyl-7-oxabicyclo<2.2.1>heptene-exo-2,3-dicarboxylic anhydride

1-methyl-7-oxa-bicyclo[2.2.1]heptane-2endo,3endo-dicarboxylic acid anhydride

2-methylfuran

1-methyl-7-oxa-bicyclo[2.2.1]heptane-2,3-dicarboxylic acid anhydride

Downstream raw materials:

N-(4-chloro-2-fluoro-5-isopropoxyphenyl)-3-methyl-3,4,5,6-tetrahydrophthalic acid imide

Refernces

• 1、 Thiyagarajan, Shanmugam,Genuino, Homer C.,Van Der Waal, Jan C.,De Jong, Ed,Weckhuysen, Bert M.,Van Haveren, Jacco,Bruijnincx, Pieter C. A.,Van Es, Daan S.. "A Facile Solid-Phase Route to Renewable Aromatic Chemicals from Biobased Furanics". . p. 1368 - 1371. Retrieved 2016/02/12.
• 2、 Thiyagarajan, Shanmugam,Genuino, Homer C.,?liwa, Micha?,Van Der Waal, Jan C.,De Jong, Ed,Van Haveren, Jacco,Weckhuysen, Bert M.,Bruijnincx, Pieter C. A.,Van Es, Daan S.. "Substituted Phthalic Anhydrides from Biobased Furanics: A New Approach to Renewable Aromatics". . p. 3052 - 3056. Retrieved 2015/09/28.