Diethylphenylphosphine oxide

Base Information

• Chemical Name: Diethylphenylphosphine oxide
• CAS No.: 24323-92-0
• Molecular Formula: C10H15OP
• Molecular Weight: 182.202
• DSSTox Substance ID: DTXSID20509146
• Nikkaji Number: J687.390A
• Wikidata: Q82366525
• Mol file: 24323-92-0.mol

Synonyms:diethylphenylphosphine oxide;24323-92-0;SCHEMBL778908;DTXSID20509146;Diethyl(oxo)phenyl-lambda~5~-phosphane

Chemical Property of Diethylphenylphosphine oxide

Chemical Property:

• XLogP3: 1.7
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 3
• Exact Mass: 182.086052095
• Heavy Atom Count: 12
• Complexity: 163

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCP(=O)(CC)C1=CC=CC=C1

Technology Process of Diethylphenylphosphine oxide

There total 23 articles about Diethylphenylphosphine oxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

ethylmagnesium bromide (925-90-6) + Triphenylphosphine oxide (791-28-6) → diethylphenylphosphine oxide (24323-92-0) + ethydiphenylphosphine oxide (1733-57-9)

Guidance literature:

In tetrahydrofuran; diethyl ether; at -78 - 20 ℃; for 24h; Inert atmosphere; Schlenk technique;

DOI:10.1016/j.tet.2015.12.043

Reference yield:

ethanol (64-17-5) + benzhydrylidene-(diethyl-phenyl-phosphoranylidene)-hydrazine → benzophenone hydrazone (5350-57-2) + diethylphenylphosphine oxide (24323-92-0)

Guidance literature:

Reference yield:

N-(diethyl-phenyl-phosphoranyliden)-aniline (16984-73-9) + methylammonium carbonate (15719-64-9,15719-76-3,97762-63-5) → diethylphenylphosphine oxide (24323-92-0) + phenyl isocyanate (103-71-9)

Guidance literature:

upstream raw materials:

ethanol

(diethyl-phenyl-phosphoranylidene)-fluoren-9-ylidene-hydrazine

N-(diethyl-phenyl-phosphoranyliden)-aniline

methylammonium carbonate

Downstream raw materials:

cyclohexyldiethylphosphine oxide

diethyl-phenyl-phosphine

1-(1-tert-Butyl-2,2-diethyl-diphosphanyl)-2,2-dimethyl-propan-1-one

Refernces

• 1、 Kendall, Alexander J.,Salazar, Chase A.,Martino, Patrick F.,Tyler, David R.. "Direct conversion of phosphonates to phosphine oxides: An improved synthetic route to phosphines including the first synthesis of methyl JohnPhos". supporting information. p. 6171 - 6178. Retrieved 2015/02/19.
• 2、 Fukuzumi, Shunichi,Shimoosako, Kanji,Suenobu, Tomoyoshi,Watanabe, Yoshihito. "Mechanisms of hydrogen-, oxygen-, and electron-transfer reactions of cumylperoxyl radical". . p. 9074 - 9082. Retrieved 2007/10/03.