Ac-(R)-β³hVal-(S)-β³hAla-(S)-β³hLys-(S)-β³hIle-(S)-β³hAla-(R)-β³hSer-(S)-β³hTyr-OH

Base Information

• Chemical Name: Ac-(R)-β³hVal-(S)-β³hAla-(S)-β³hLys-(S)-β³hIle-(S)-β³hAla-(R)-β³hSer-(S)-β³hTyr-OH
• CAS No.: 1207335-57-6
• Molecular Formula: C₄₄H₇₄N₈O₁₁
• Molecular Weight: 891.119
• Mol file: 1207335-57-6.mol

Synonyms:

Chemical Property of Ac-(R)-β³hVal-(S)-β³hAla-(S)-β³hLys-(S)-β³hIle-(S)-β³hAla-(R)-β³hSer-(S)-β³hTyr-OH

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Ac-(R)-β³hVal-(S)-β³hAla-(S)-β³hLys-(S)-β³hIle-(S)-β³hAla-(R)-β³hSer-(S)-β³hTyr-OH

There total 1 articles about Ac-(R)-β³hVal-(S)-β³hAla-(S)-β³hLys-(S)-β³hIle-(S)-β³hAla-(R)-β³hSer-(S)-β³hTyr-OH which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

acetic anhydride (108-24-7) + Fmoc-β3-HVal (172695-33-9) + (S)-3-(9H-fluoren-9-ylmethoxycarbonylamino)butyric acid (193954-26-6) + Fmoc-β3-HIle-OH (193954-27-7) + Fmoc-β3-O-t-butyl-L-homoserine (203854-51-7) + Fmoc-(S)-β3-HLys(Boc)-OH (203854-47-1) + (S)-3-(<<(9H-fluoren-9-yl)methoxy>carbonyl>amino)-4-<4-(tert-butoxy)phenyl>butanoic acid (219967-69-8) → Ac-(R)-β3hVal-(S)-β3hAla-(S)-β3hLys-(S)-β3hIle-(S)-β3hAla-(R)-β3hSer-(S)-β3hTyr-OH (1207335-57-6)

Guidance literature:

(S)-3-(<<(9H-fluoren-9-yl)methoxy>carbonyl>amino)-4-<4-(tert-butoxy)phenyl>butanoic acid; With 1-methyl-1H-imidazole; In dichloromethane; for 4h; Inert atmosphere;

With piperidine; In N,N-dimethyl-formamide; Inert atmosphere;

acetic anhydride; Fmoc-β³-HVal; (S)-3-(9H-fluoren-9-ylmethoxycarbonylamino)butyric acid; Fmoc-β³-HIle-OH; Fmoc-β³-O-t-butyl-L-homoserine; Fmoc-(S)-β³-HLys(Boc)-OH; Further stages;

DOI:10.1002/hlca.200900325

upstream raw materials:

acetic anhydride

Fmoc-β³-HVal

(S)-3-(9H-fluoren-9-ylmethoxycarbonylamino)butyric acid

Fmoc-β³-HIle-OH

Refernces