Methanone, (4-hydroxy-1-naphthalenyl)phenyl-

Base Information

• Chemical Name: Methanone, (4-hydroxy-1-naphthalenyl)phenyl-
• CAS No.: 24776-44-1
• Molecular Formula: C17H12O2
• Molecular Weight: 248.281
• DSSTox Substance ID: DTXSID10471803
• Nikkaji Number: J765.323I
• Wikidata: Q82300463
• Mol file: 24776-44-1.mol

Synonyms:24776-44-1;Methanone, (4-hydroxy-1-naphthalenyl)phenyl-;(4-hydroxynaphthalen-1-yl)(phenyl)methanone;SCHEMBL7915213;4-BENZOYLNAPHTHALEN-1-OL;DTXSID10471803;AKOS019823970;(4-hydroxy-1-naphthalenyl)phenylmethanone;EN300-1276405

Chemical Property of Methanone, (4-hydroxy-1-naphthalenyl)phenyl-

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C
• XLogP3: 4.7
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 248.083729621
• Heavy Atom Count: 19
• Complexity: 319

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C(=O)C2=CC=C(C3=CC=CC=C32)O

Technology Process of Methanone, (4-hydroxy-1-naphthalenyl)phenyl-

There total 20 articles about Methanone, (4-hydroxy-1-naphthalenyl)phenyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

1-benzoyl-4-methoxynaphthalene (24776-45-2) → 4-benzoyl-1-naphthol (24776-44-1)

Guidance literature:

With potassium hydride; In dimethyl sulfoxide; at 95 ℃; for 20h;

DOI:10.1021/jo972351a

Reference yield: 88.0%

α-naphthol (90-15-3) + benzoyl chloride (98-88-4) → 4-benzoyl-1-naphthol (24776-44-1)

Guidance literature:

With aluminium trichloride; In nitrobenzene; 1.) 0 deg C, 2.) 10 deg C, 19 h;

Reference yield: 48.0%

α-naphthyl benzoate (607-55-6) → 2-benzoyl-1-naphthol (21009-99-4) + 4-benzoyl-1-naphthol (24776-44-1)

Guidance literature:

In methanol; for 17h; Irradiation;

DOI:10.1016/j.tet.2004.11.022

upstream raw materials:

α-naphthyl benzoate

α-naphthol

benzoyl chloride

Benzotrichlorid

Downstream raw materials:

4-(phenylmethyl)-1-naphthalenol

1-(4-Benzoyl-1-naphthoxy)-butanon-⁽²⁾

α-naphthol

benzoic acid

Refernces

• 1、 Jain, Nikita,Xu, Sanjia,Ciufolini, Marco A.. "Asymmetric Oxidative Cycloetherification of Naphtholic Alcohols". supporting information. p. 4542 - 4546. Retrieved 2017/04/13.
• 2、 Kaanumalle, Lakshmi S.,Gibb, Corinne L. D.,Gibb, Bruce C.,Ramamurthy. "Photo-Fries reaction in water made selective with a capsule". . p. 236 - 238. Retrieved 2008/03/14.