N-benzyl-N-methylprop-2-en-1-amine

Base Information

• Chemical Name: N-benzyl-N-methylprop-2-en-1-amine
• CAS No.: 2520-97-0
• Molecular Formula: C11H15N
• Molecular Weight: 161.247
• European Community (EC) Number: 662-294-2
• ChEMBL ID: CHEMBL26026
• Nikkaji Number: J697.634D
• Mol file: 2520-97-0.mol

Synonyms:N-benzyl-N-methylprop-2-en-1-amine;vinylbenzyldimethylamine;2520-97-0;CHEMBL26026;SCHEMBL185582;N-benzyl-N-methyl-2-propen-1-amine;AKOS023091245;NYP

Chemical Property of N-benzyl-N-methylprop-2-en-1-amine

Chemical Property:

• XLogP3: 2.6
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 4
• Exact Mass: 161.120449483
• Heavy Atom Count: 12
• Complexity: 125

Purity/Quality:

95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CN(CC=C)CC1=CC=CC=C1

Technology Process of N-benzyl-N-methylprop-2-en-1-amine

There total 19 articles about N-benzyl-N-methylprop-2-en-1-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

methanol (67-56-1) + Allylbenzylamine (4383-22-6) → N-allyl-N-α-methylbenzylamine (2520-97-0)

Guidance literature:

With 5percent silver supported on titanium oxide; at 25 ℃; for 24h; Inert atmosphere; Sealed tube; UV-irradiation;

Reference yield: 96.0%

prop-2-en-1-yl benzyl(methyl)carbamate (152507-72-7) → N-allyl-N-α-methylbenzylamine (2520-97-0) + benzyl-methyl-amine (103-67-3)

Guidance literature:

With diethylamine; palladium diacetate; trisodium tris(3-sulfophenyl)phosphine; In water; at 20 ℃; for 0.0833333h;

DOI:10.1016/S0040-4039(00)60524-5

Reference yield: 96.0%

allyl alcohol (107-18-6) + benzyl-methyl-amine (103-67-3) → N-allyl-N-α-methylbenzylamine (2520-97-0)

Guidance literature:

With ammonium hexafluorophosphate; [Pt(η3-C3H5)(DPP-Xantphos)]PF6; In toluene; acetonitrile; at 50 ℃; for 4h; Inert atmosphere;

DOI:10.1002/chem.200801197

upstream raw materials:

Allylbenzylamine

trimethylstannylmethyl iodide

tri-n-butylstannylmethyl iodide

allyl bromide

Downstream raw materials:

benzyl-methyl-amine

5-allyl-1,2,3,4,5-penta(4-acetylphenyl)cyclopentadiene

N-allyl-N-methyl-4-toluene sulphonamide

N-benzyl-N-methyl cyanamide

Refernces

• 1、 Gong, Mingliang,Guo, Chenjun,Jiang, Linhong,Luo, Yunjie,Yu, Chong. "Deoxygenation of primary amides to amines with pinacolborane catalyzed by Ca[N(SiMe3)2]2(THF)2". supporting information. p. 1201 - 1206. Retrieved 2021/05/29.
• 2、 Targos, Karina,Wang, Diana J.,Wickens, Zachary K.. "Electrochemical Synthesis of Allylic Amines from Terminal Alkenes and Secondary Amines". supporting information. p. 21503 - 21510. Retrieved 2022/01/03.