N,3-DIPHENYLACRYLAMIDE

Base Information

• Chemical Name: N,3-DIPHENYLACRYLAMIDE
• CAS No.: 25775-89-7
• Molecular Formula: C₁₅H₁₃NO
• Molecular Weight: 223.274
• Mol file: 25775-89-7.mol

Synonyms:AURORA KA-3355;(2E)-N,3-DIPHENYLACRYLAMIDE;N-phenylcinnamide;N-phenyl-3-phenylpropenamide;N-cinnamoylaniline;N-PHENYLCINNAMAMIDE;3,N-diphenylacrylamide;Zintsaeureanilid;2-PropenaMide,3-phenyl-N-phenyl-,(2E);N,3-diphenylacrylamide (en);

Chemical Property of N,3-DIPHENYLACRYLAMIDE

Chemical Property:

• PSA: 29.10000
• LogP: 3.41150

Purity/Quality:

98%min ^*data from raw suppliers

N,3-Diphenylacrylamide >95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of N,3-DIPHENYLACRYLAMIDE

There total 57 articles about N,3-DIPHENYLACRYLAMIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

cinnamoyl chloride (102-92-1,17082-09-6) + aniline (62-53-3) → cinnamanilide (3056-73-3,25775-89-7,52393-67-6)

Guidance literature:

With pyridine; In toluene; for 12h;

DOI:10.1007/BF00777140

Reference yield: 95.0%

aniline (62-53-3) + methyl cinnamate (103-26-4,1754-62-7) → cinnamanilide (3056-73-3,25775-89-7,52393-67-6)

Guidance literature:

With aluminum (III) chloride; triethylamine; at 25 ℃; for 1h; chemoselective reaction;

DOI:10.1007/s11164-012-0517-x

Reference yield: 93.0%

Cinnamic acid (621-82-9) + aniline (62-53-3) → cinnamanilide (3056-73-3,25775-89-7,52393-67-6)

Guidance literature:

With 1-methyl-pyrrolidin-2-one; 3,3'-(phenylphosphinylidene)bis<2(3H)-benzothiazolone; triethylamine; Ambient temperature;

DOI:10.1246/bcsj.58.3291

upstream raw materials:

chalcone oxime

cinnamoyl chloride

aniline

cinnamic acid anhydride

Downstream raw materials:

(E)-3-phenylpropenal

hydrocinnamanilide

α,β-dibromohydrocinnamanilide

N-phenyl-cinnamimidoyl chloride

Refernces

• 1、 Hernandez, Elisa,Hoberg, Heinz. "CC-Verknuepfung von Styrol mit Isocyanaten an Nickel(0), eine Katalytische Synthese von Zimtsaeureamiden". . p. 245 - 254. Retrieved 1986.
• 2、 Liu, Feng,Wu, Na,Cheng, Xu. "Chlorination Reaction of Aromatic Compounds and Unsaturated Carbon-Carbon Bonds with Chlorine on Demand". supporting information. p. 3015 - 3020. Retrieved 2021/05/05.
• 3、 Fu, Zhengqiang,Wang, Xinghua,Tao, Sheng,Bu, Qingqing,Wei, Donghui,Liu, Ning. "Manganese Catalyzed Direct Amidation of Esters with Amines". . p. 2339 - 2358. Retrieved 2021/02/03.