Pentanamide, 2-(acetylamino)-N,4-dimethyl-

Base Information

• Chemical Name: Pentanamide, 2-(acetylamino)-N,4-dimethyl-
• CAS No.: 26090-94-8
• Molecular Formula: C9H18N2O2
• Molecular Weight: 186.25100
• DSSTox Substance ID: DTXSID20405614
• Mol file: 26090-94-8.mol

Synonyms:N-Acetyl-L-leucine-N-methylamide-d16;1276197-56-8;Pentanamide, 2-(acetylamino)-N,4-dimethyl-;26090-94-8;(2S)-2-(acetylamino)-N,4-dimethylpentanamide;N-acetyl-dl-leucine methylamide;DTXSID20405614;AKOS009615503;FT-0693691

Chemical Property of Pentanamide, 2-(acetylamino)-N,4-dimethyl-

Chemical Property:

• Vapor Pressure: 6.71E-07mmHg at 25°C
• Boiling Point: 409oC at 760 mmHg
• PKA: 14.62±0.46(Predicted)
• Flash Point: 176.4oC
• PSA: 65.18000
• Density: 0.981g/cm3
• LogP: 1.96380
• XLogP3: 0.1
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 4
• Exact Mass: 186.136827821
• Heavy Atom Count: 13
• Complexity: 190

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C)CC(C(=O)NC)NC(=O)C

Technology Process of Pentanamide, 2-(acetylamino)-N,4-dimethyl-

There total 3 articles about Pentanamide, 2-(acetylamino)-N,4-dimethyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

ethyl N-acetyl-leucinate (4071-36-7) → N-acetyl-N'-methylleucinamide (26090-94-8)

Guidance literature:

With methanol;

DOI:10.1021/ja01138a058

Reference yield:

N-Ac-Leu (1188-21-2) + acetic anhydride (108-24-7) → N-acetyl-N'-methylleucinamide (26090-94-8)

Guidance literature:

Behandeln des Reaktionsprodukts mit Methylamin in Aether;

DOI:10.1021/ja01147a142

Reference yield:

→ N-acetyl-N'-methylleucinamide (26090-94-8)

Guidance literature:

Acetyl-DL-leucin, Triethylamin, Isobutylchlorformiat, Methylamin, THF;

DOI:10.1002/bip.360100612

upstream raw materials:

N-Ac-Leu

acetic anhydride

ethyl N-acetyl-leucinate