Technology Process of Benzenepropanoic acid,
2-(2-methylpropoxy)-5-[4-(2-methylpropoxy)benzoyl]-
There total 10 articles about Benzenepropanoic acid,
2-(2-methylpropoxy)-5-[4-(2-methylpropoxy)benzoyl]- which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
sodium hydroxide;
at 60 ℃;
for 2h;
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: 73 percent / NaClO2; aq. H2O2; NaH2PO4 / acetonitrile / 1 h / 20 °C
2.1: oxalyl chloride; DMF / CH2Cl2 / 1 h / 20 °C
2.2: 80 percent / AlCl3 / CH2Cl2 / 0.5 h / 5 - 10 °C
3.1: aq. NaOH / acetone / 2 h / 50 °C
With
sodium hydroxide; sodium chlorite; sodium dihydrogenphosphate; oxalyl dichloride; dihydrogen peroxide; N,N-dimethyl-formamide;
In
dichloromethane; acetone; acetonitrile;
2.2: Friedel-Crafts reaction;
DOI:10.1021/jm050550d
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: AlCl3 / CH2Cl2 / 1 h / -10 °C
1.2: CH2Cl2 / 2 h / Heating
2.1: 73 percent / NaClO2; aq. H2O2; NaH2PO4 / acetonitrile / 1 h / 20 °C
3.1: oxalyl chloride; DMF / CH2Cl2 / 1 h / 20 °C
3.2: 80 percent / AlCl3 / CH2Cl2 / 0.5 h / 5 - 10 °C
4.1: aq. NaOH / acetone / 2 h / 50 °C
With
sodium hydroxide; sodium chlorite; sodium dihydrogenphosphate; aluminium trichloride; oxalyl dichloride; dihydrogen peroxide; N,N-dimethyl-formamide;
In
dichloromethane; acetone; acetonitrile;
1.1: Friedel-Crafts reaction / 3.2: Friedel-Crafts reaction;
DOI:10.1021/jm050550d