1,5-Octanediol

Base Information

• Chemical Name: 1,5-Octanediol
• CAS No.: 2736-67-6
• Molecular Formula: C8H18O2
• Molecular Weight: 146.23
• Mol file: 2736-67-6.mol

Synonyms:octane-1,5-diol;Octan-1,5-diol;1,5-Octandiol;

Chemical Property of 1,5-Octanediol

Chemical Property:

• Boiling Point: 144-146 °C
• PSA: 40.46000
• Density: 0.950 g/cm3(Temp: 17 °C)
• LogP: 1.31000

Purity/Quality:

95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1,5-Octanediol

There total 1 articles about 1,5-Octanediol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 11.0%

1,7-Octadiene (3710-30-3) → 1,8-Octanediol (629-41-4) + (5RS)-octane-1,5-diol (2736-67-6)

Guidance literature:

With 9-borabicyclo[3.3.1]nonane dimer; dimethylsulfide borane complex; Product distribution;

DOI:10.1021/jo00180a023

Reference yield: 95.0%

(5RS)-octane-1,5-diol (2736-67-6) + 2',3',4',5',6'-pentamethylacetophenone (2040-01-9) → (2,3,4,5,6-pentamethylphenyl)(2-propylcyclohex-1-en-1-yl)methanone

Guidance literature:

With bis(1,5-cyclooctadiene)diiridium(I) dichloride; potassium hydroxide; catacxium A; In toluene; at 115 ℃; for 24h; chemoselective reaction; Sealed tube;

DOI:10.1021/jacs.9b12296

Reference yield:

(5RS)-octane-1,5-diol (2736-67-6) → C20H36N2O5SSi

Guidance literature:

Multi-step reaction with 5 steps

1: N,N-dimethyl-formamide / 40 °C

2: tetrabutyl ammonium fluoride; triethylamine / tetrahydrofuran / 0 °C

3: triphenylphosphine; diethylazodicarboxylate / tetrahydrofuran / 0 °C

4: palladium on activated charcoal; hydrogen / methanol / 20 °C

5: triethylamine / dichloromethane / 0 °C

With palladium on activated charcoal; tetrabutyl ammonium fluoride; hydrogen; triethylamine; triphenylphosphine; diethylazodicarboxylate; In tetrahydrofuran; methanol; dichloromethane; N,N-dimethyl-formamide;

DOI:10.1002/anie.201608210

upstream raw materials:

1,7-Octadiene

Refernces