2-(4-Nitrophenyl)furan

Base Information

• Chemical Name: 2-(4-Nitrophenyl)furan
• CAS No.: 28123-72-0
• Molecular Formula: C10H7NO3
• Molecular Weight: 189.17
• Hs Code.: 2932190090
• Mol file: 28123-72-0.mol

Synonyms:Furan,2-(4-nitrophenyl);2-(4-nitrophenyl) furan;

Chemical Property of 2-(4-Nitrophenyl)furan

Chemical Property:

• Melting Point: 134-135 °C
• Boiling Point: 309.9±17.0 °C(Predicted)
• PSA: 58.96000
• Density: 1.266±0.06 g/cm3(Predicted)
• LogP: 3.37800

Purity/Quality:

97.0% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-(4-Nitrophenyl)furan

There total 34 articles about 2-(4-Nitrophenyl)furan which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

2-(tributylstannyl)furan (118486-94-5) + para-nitrophenyl bromide (586-78-7) → 2-(4-nitrophenyl)furan (28123-72-0)

Guidance literature:

With 1,4-diaza-bicyclo[2.2.2]octane; tetrabutyl ammonium fluoride; palladium diacetate; In 1,4-dioxane; at 100 ℃; for 16h;

DOI:10.1021/jo048066q

Reference yield: 100.0%

p-nitrobenzene iodide (636-98-6) + 2-(tributylstannyl)furan (118486-94-5) → 2-(4-nitrophenyl)furan (28123-72-0)

Guidance literature:

With potassium fluoride; 1,4-dicyclohexyl-diazabutadiene; bis(dibenzylideneacetone)-palladium⁽⁰⁾; In 1,4-dioxane; at 100 ℃; for 16h;

DOI:10.1016/j.tet.2005.04.073

Reference yield: 97.0%

furan (110-00-9) + 4-nitro-aniline (100-01-6,104810-17-5) → 2-(4-nitrophenyl)furan (28123-72-0)

Guidance literature:

4-nitro-aniline; With tetrafluoroboric acid; sodium nitrite; In water; at 0 ℃; for 0.666667h;

furan; With bismuth(III) oxide; In N,N-dimethyl-formamide; for 15h; Inert atmosphere; Sealed tube; Irradiation;

DOI:10.1002/ejoc.201701242

upstream raw materials:

5-(4-nitrophenyl)-furan-2-carboxylic acid

furan

4-nitrophenyl sulfurofluoridate

4-nitrobenzenediazonium tetrafluoroborate

Downstream raw materials:

4-(furan-2-yl)aniline

5-methoxy-2-(4-nitrophenyl)furan

Bis<2-(p-nitrophenyl)furyl-5>methane

Dimethyl-[5-(4-nitro-phenyl)-furan-2-ylmethyl]-amine

Refernces

• 1、 Kundu, Abhishek,Dey, Dhananjay,Pal, Subhankar,Adhikari, Debashis. "Pyrazole-Mediated C-H Functionalization of Arene and Heteroarenes for Aryl-(Hetero)aryl Cross-Coupling Reactions". . p. 15665 - 15673. Retrieved 2021/11/16.
• 2、 Chan, Bun,McErlean, Christopher S. P.,Nashar, Philippe E.,Tatunashvili, Elene. "σ-Bond initiated generation of aryl radicals from aryl diazonium salts". supporting information. p. 1812 - 1819. Retrieved 2020/03/17.