NSC45356

Base Information

• Chemical Name: NSC45356
• CAS No.: 3775-60-8
• Molecular Formula: C2H3 N3 O
• Molecular Weight: 85.0653
• Hs Code.: 2934999090
• Mol file: 3775-60-8.mol

Synonyms:1,3,4-Oxadiazole,2-amino- (6CI,7CI,8CI); 2-Amino-1,3,4-oxadiazole; 5-Imino-D2-1,3,4-oxadiazoline; NSC 45356

Chemical Property of NSC45356

Chemical Property:

• Vapor Pressure: 0.247mmHg at 25°C
• Melting Point: 156 °C
• Boiling Point: 205.6°C at 760 mmHg
• PKA: -0.75±0.10(Predicted)
• Flash Point: 78.2°C
• PSA: 64.94000
• Density: 1.395g/cm³
• LogP: 0.23300
• Storage Temp.: 2-8°C(protect from light)

Purity/Quality:

99%, ^*data from raw suppliers

1,3,4-oxadiazol-2-amine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of NSC45356

There total 9 articles about NSC45356 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 55.0%

2-Amino-5-acetyl-1,3,4-oxadiazol (74949-72-7) + 1,2-diamino-benzene (95-54-5) → 1,3,4-oxadiazol-2-amine (3775-60-8) + 2-Methyl-1H-benzimidazole (615-15-6) + 2-Methyl-3-semicarbazido-chinoxalin (79015-02-4)

Guidance literature:

With hydrogenchloride; In ethanol; for 0.5h; Heating;

Reference yield:

bromocyane (506-68-3) + formic acid hydrazide (624-84-0) → 1,3,4-oxadiazol-2-amine (3775-60-8)

Guidance literature:

Reference yield:

5-amino[1,3,4]oxadiazole-2-carboxylic acid ethyl ester (4970-53-0) → 1,3,4-oxadiazol-2-amine (3775-60-8)

Guidance literature:

With sodium hydroxide; In water; for 0.0833333h;

upstream raw materials:

bromocyane

formic acid hydrazide

2-Amino-5-acetyl-1,3,4-oxadiazol

1,2-diamino-benzene

Downstream raw materials:

4-[(2R)-1-(1,3,4-oxadiazol-2-ylamino)-1-oxopropan-2-yl]phenyl trifluoromethanesulfonate

(triphenyl-λ⁵-phosphanylidene)-[1,3,4]oxadiazol-2-yl-amine

1-[1,3,4]oxadiazol-2-yl-3-phenyl-urea

Refernces

• 1、 -. "HETEROCYCLIC AMIDE COMPOUND". Paragraph 0235. . Retrieved 2020/10/31.
• 2、 -. "The heterocyclic amide compound (by machine translation)". Paragraph 0224. . Retrieved 2017/06/24.