(E)-3-Aminoacrylaldehyde

Base Information

• Chemical Name: (E)-3-Aminoacrylaldehyde
• CAS No.: 28636-16-0
• Molecular Formula: C3H5NO
• Molecular Weight: 71.07790
• Mol file: 28636-16-0.mol

Synonyms:3-amino acrolein;3-aminoacrolein;β-aminoacrolein;

Chemical Property of (E)-3-Aminoacrylaldehyde

Chemical Property:

• PSA: 43.09000
• LogP: 0.35800

Purity/Quality:

99% ^*data from raw suppliers

(E)-3-aminoprop-2-enal ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (E)-3-Aminoacrylaldehyde

There total 2 articles about (E)-3-Aminoacrylaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Malondialdehyde (542-78-9) → β-aminoacrolein (76063-24-6) + 3-aminoacrylaldehyde (28636-16-0)

Guidance literature:

With ammonia; Title compound not separated from byproducts;

DOI:10.1002/(SICI)1097-458X(199803)36:3<154::AID-OMR232>3.0.CO;2-0

Reference yield:

→ 3-aminoacrylaldehyde (28636-16-0)

Guidance literature:

DOI:10.1016/0022-2860(69)80062-1

Reference yield:

3-aminoacrylaldehyde (28636-16-0) + nitromalonic aldehyde sodium salt (2940-26-3) → 5-nitronicotinaldehyde (87883-20-3)

Guidance literature:

With pyridine; p-toluenesulfonyl chloride; Yield given. Multistep reaction; 1. dimethylformamide, -5 deg C 2. DMF, 2h;

DOI:10.1021/jo00175a048

upstream raw materials:

Malondialdehyde

Downstream raw materials:

5-nitronicotinaldehyde

Refernces

• 1、 Gomez-Sanchez, Antonio,Paredes-Leon, Rocio,Campora, Juan. "1H and 13C NMR spectra and isomerism of 3-aminoacroleins". . p. 154 - 162. Retrieved 2007/10/03.