Welcome to LookChem.com Sign In|Join Free
  • or
Home > Products >  > 

Propyphenazone

Related Products

Hot Products

Basic Information Post buying leads Suppliers
Name

Propyphenazone

EINECS 207-539-2
CAS No. 479-92-5 Density 1.081 g/cm3
PSA 26.93000 LogP 2.60780
Solubility 743.6g/L(25.35 oC) Melting Point 102-105 °C
Formula C14H18N2O Boiling Point 319 °C at 760 mmHg
Molecular Weight 230.31 Flash Point 123.8 °C
Transport Information N/A Appearance solid
Safety 26-36/37/39 Risk Codes 36/37/38
Molecular Structure Molecular Structure of 479-92-5 (Propyphenazone) Hazard Symbols Xn
Synonyms

Antipyrine,4-isopropyl- (6CI,7CI,8CI);1,2-Dihydro-1,5-dimethyl-2-phenyl-4-isopropyl-3H-pyrazol-3-one;1-Phenyl-2,3-dimethyl-4-isopropyl-3-pyrazolin-5-one;1-Phenyl-2,3-dimethyl-4-isopropylpyrazol-5-one;4-Isopropyl-2,3-dimethyl-1-phenyl-3-pyrazolin-5-one;4-Isopropylantipyrine;4-Isopropylphenazone;Arantil P;Budirol;Causyth;Cibalgina;Eufibron;Isopropchin;Isopropylantipyrin;Isopropylantipyrine;Isopropylphenazone;Isopropyrine;Larodon;

 

Propyphenazone Consensus Reports

Reported in EPA TSCA Inventory.

Propyphenazone Specification

The 4-Isopropylantipyrine is an organic compound with the formula C14H18N2O. The IUPAC name of this chemical is 1,5-dimethyl-2-phenyl-4-propan-2-ylpyrazol-3-one. With the CAS registry number 479-92-5, it is also named as 1,2-Dihydro-1,5-dimethyl-4-(1-methylethyl)-2-phenyl-3H-pyrazol-3-one. The product's categories are Active Pharmaceutical Ingredients; API's. Besides, it should be stored in a cool closed and well-ventilated place.

Physical properties about 4-Isopropylantipyrine are: (1)ACD/LogP: 1.74; (2)ACD/LogD (pH 5.5): 1.74; (3)ACD/LogD (pH 7.4): 1.74; (4)ACD/BCF (pH 5.5): 12.31; (5)ACD/BCF (pH 7.4): 12.31; (6)ACD/KOC (pH 5.5): 209.95; (7)ACD/KOC (pH 7.4): 209.96; (8)#H bond acceptors: 3; (9)#Freely Rotating Bonds: 2; (10)Polar Surface Area: 23.55 Å2; (11)Index of Refraction: 1.555; (12)Molar Refractivity: 68.41 cm3; (13)Molar Volume: 212.8 cm3; (14)Polarizability: 27.12×10-24cm3; (15)Surface Tension: 38.5 dyne/cm; (16)Density: 1.081 g/cm3; (17)Flash Point: 123.8 °C; (18)Enthalpy of Vaporization: 56.06 kJ/mol; (19)Boiling Point: 319 °C at 760 mmHg; (20)Vapour Pressure: 0.000347 mmHg at 25°C.

When you are using this chemical, please be cautious about it as the following:
This chemical is irritating to eyes, respiratory system and skin. When you are using it, wear suitable gloves and eye/face protection. In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.

You can still convert the following datas into molecular structure:
(1)SMILES: O=C2\C(=C(/N(N2c1ccccc1)C)C)C(C)C
(2)InChI: InChI=1/C14H18N2O/c1-10(2)13-11(3)15(4)16(14(13)17)12-8-6-5-7-9-12/h5-10H,1-4H3
(3)InChIKey: PXWLVJLKJGVOKE-UHFFFAOYAH
(4)Std. InChI: InChI=1S/C14H18N2O/c1-10(2)13-11(3)15(4)16(14(13)17)12-8-6-5-7-9-12/h5-10H,1-4H3
(5)Std. InChIKey: PXWLVJLKJGVOKE-UHFFFAOYSA-N

The toxicity data is as follows:

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
cat LDLo oral 150mg/kg (150mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: EXCITEMENT
Journal of Pharmacology and Experimental Therapeutics. Vol. 61, Pg. 205, 1937.
guinea pig LD50 oral 1050mg/kg (1050mg/kg)   Schweizerische Medizinische Wochenschrift. Vol. 84, Pg. 351, 1954.
mouse LD50 intraperitoneal 295mg/kg (295mg/kg)   Archives Internationales de Pharmacodynamie et de Therapie. Vol. 122, Pg. 434, 1959.
mouse LD50 oral 960mg/kg (960mg/kg)   Arzneimittel-Forschung. Drug Research. Vol. 9, Pg. 401, 1959.
rabbit LDLo oral 500mg/kg (500mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: EXCITEMENT
Journal of Pharmacology and Experimental Therapeutics. Vol. 61, Pg. 205, 1937.
rat LD50 oral 860mg/kg (860mg/kg)   Yakugaku Zasshi. Journal of Pharmacy. Vol. 97, Pg. 601, 1977.

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 479-92-5