- Pyridine hydrofluoride
- Pyridine iodine monochloride complex
- Pyridine methanesulfonate
- Pyridine sulfur trioxide
- Pyridine trifluoroacetate
- Pyridine, 2-(2,4-difluorophenoxy)-3-nitro-
- Pyridine, 2-(3-azetidinyl)- (9CI)
- Pyridine, 2-(3-bromophenyl)-
- Pyridine, 2,3,4,5-tetrahydro-6-(1-propenyl)-, (E)-
- Pyridine, 2,3-diiodo-
- 457-60-3Sulfoxylic acid,mono[[[5-[(3-amino-4-hydroxyphenyl)diarsenyl]-2-hydroxyphenyl]amino]methyl]ester, sodium salt (1:1)
- 457613-78-41-Piperazinecarboxylic acid, 4-(4-boronophenyl)-, 1-(1,1-dimethylethyl) ester
- 457633-17-9L-Arginine,L-arginyl-6-aminohexanoyl-L-arginyl-6-aminohexanoyl-L-arginyl-6-aminohexanoyl-L-arginyl-6-aminohexanoyl-L-arginyl-6-aminohexanoyl-L-arginyl-6-aminohexanoyl-
- 45766-35-6isoindolin-5-amine
- 45767-66-6Benzene,1-(bromomethyl)-2-chloro-4-fluoro-
- 457-68-1Benzene,1,1'-methylenebis[4-fluoro-
- 4576-90-33-Isothiazolecarboxylicacid
- 4578-31-85'-Adenylic acid,sodium salt (1:2)
- 457889-46-2[1,1'-Biphenyl]-4-methanol,4'-(trifluoromethyl)-
- 45791-36-4Benzenemethanamine,4-bromo-a-methyl-, (aR)-
Hot Products
- 104987-11-3Tacrolimus
- 141-53-7Sodium formate
- 8001-54-5Quaternary ammonium compounds, alkylbenzyldimethyl, chlorides
- 9003-39-8Povidone
- 10161-34-9Trenbolone acetate
- 402957-28-2Telaprevir
- 68-19-9Cyanocobalamin
- 7631-86-9Silicon dioxide
- 302-79-4Tretinoin
- 77-92-9Citric acid
|
Basic Information |
|
Post buying leads |
|
Suppliers |
|
Cas Database |
| Name |
Pyridine,2,3-bis(chloromethyl)- |
EINECS | N/A |
| CAS No. | 45754-12-9 | Density | 1.275 g/cm3 |
| PSA | 12.89000 | LogP | 2.55920 |
| Solubility | N/A | Melting Point |
N/A |
| Formula | C7H7 Cl2 N | Boiling Point | 264.48 ºC at 760 mmHg |
| Molecular Weight | 176.045 | Flash Point | 139.294 ºC |
| Transport Information | N/A | Appearance | N/A |
| Safety | Risk Codes | N/A | |
| Molecular Structure |
|
Hazard Symbols | N/A |
| Synonyms |
2,3-Bis(chloromethyl)pyridine; |
Article Data | 9 |
Pyridine,2,3-bis(chloromethyl)- Synthetic route
- 423169-40-8
2,3-bis(hydroxymethyl)pyridine hydrochloride
- 45754-12-9
2,3-bis(chloromethyl)-pyridine
| Conditions | Yield |
|---|---|
| With thionyl chloride In toluene | 89% |
- 38070-79-0
2,3-bis(hydroxymethyl)pyridine
- 45754-12-9
2,3-bis(chloromethyl)-pyridine
| Conditions | Yield |
|---|---|
| With thionyl chloride In dichloromethane at 45℃; Cooling with ice; | 40% |
| With thionyl chloride In dichloromethane at 75℃; for 1h; | 26% |
| With thionyl chloride In dichloromethane Heating / reflux; | 24% |
- 2050-22-8
2,3-diethyl pyridinedicarboxylate
- 45754-12-9
2,3-bis(chloromethyl)-pyridine
| Conditions | Yield |
|---|---|
| With lithium aluminium tetrahydride; diethyl ether Erwaermen des Reaktionsprodukts mit Thionylchlorid; |
- 89-00-9
Pyridine-2,3-dicarboxylic acid
- 45754-12-9
2,3-bis(chloromethyl)-pyridine
| Conditions | Yield |
|---|---|
| Multi-step reaction with 3 steps 1: 72 percent / conc. H2SO4 / 20 h / Heating 2: 85 percent / NaBH4 / ethanol / 17 h / Heating 3: 26 percent / SOCl2 / CH2Cl2 / 1 h / 75 °C View Scheme | |
| Multi-step reaction with 3 steps 1: sulfuric acid 2: sodium tetrahydroborate; hydrogenchloride / ethanol 3: thionyl chloride / toluene View Scheme | |
| Multi-step reaction with 3 steps 1: thionyl chloride / Heating / reflux 2: sodium tetrahydroborate / ethanol; water / 20 °C 3: thionyl chloride / dichloromethane / Heating / reflux View Scheme |
- 605-38-9
dimethyl 2,3-pyridinedicarboxylate
- 45754-12-9
2,3-bis(chloromethyl)-pyridine
| Conditions | Yield |
|---|---|
| Multi-step reaction with 2 steps 1: 85 percent / NaBH4 / ethanol / 17 h / Heating 2: 26 percent / SOCl2 / CH2Cl2 / 1 h / 75 °C View Scheme | |
| Multi-step reaction with 2 steps 1: sodium tetrahydroborate; hydrogenchloride / ethanol 2: thionyl chloride / toluene View Scheme | |
| Multi-step reaction with 2 steps 1: sodium tetrahydroborate / ethanol; water / 20 °C 2: thionyl chloride / dichloromethane / Heating / reflux View Scheme | |
| Multi-step reaction with 2 steps 1: sodium tetrahydroborate / ethanol / 80 °C / Cooling with ice 2: thionyl chloride / dichloromethane / 45 °C / Cooling with ice View Scheme |
- 583-61-9
2,3-Lutidine
- 45754-12-9
2,3-bis(chloromethyl)-pyridine
- 27221-49-4
2,3-bis(chloromethyl)pyridine hydrochloride
- 45754-12-9
2,3-bis(chloromethyl)-pyridine
| Conditions | Yield |
|---|---|
| With sodium carbonate In dichloromethane; water pH=7.5 - 8; |
| Conditions | Yield |
|---|---|
| Stage #1: trimethylsilyl cyanide With cesium fluoride In acetonitrile at 10 - 20℃; for 0.5h; Stage #2: 2,3-bis(chloromethyl)-pyridine In acetonitrile at 10 - 40℃; for 12h; Temperature; Reagent/catalyst; | 98.6% |
- 45754-12-9
2,3-bis(chloromethyl)-pyridine
- 18522-92-4
sodium p-toluenesulfonamide
- 204593-50-0
6-(toluene-4-sulfonyl)-6,7-dihydro-5H-pyrrolo[3,4-b]pyridine
| Conditions | Yield |
|---|---|
| In N,N-dimethyl-formamide at 70 - 80℃; for 2.5h; | 80.5% |
- 45754-12-9
2,3-bis(chloromethyl)-pyridine
- 1056039-93-0
N-(((1S,9aS)-7-amino-3-oxo-1,3,9,9a-tetrahydrooxazolo[3,4-a]indol-1-yl)methyl)acetamide
- 1056035-14-3
N-(((1S,9aS)-3-oxo-7-(5H-pyrrolo[3,4-b]pyridin-6(7H)-yl)-1,3,9,9a-tetrahydrooxazolo[3,4-a]indol-1-yl)methyl)acetamide
| Conditions | Yield |
|---|---|
| With potassium carbonate; potassium iodide In N,N-dimethyl-formamide at 80 - 90℃; | 80% |
Pyridine,2,3-bis(chloromethyl)- Specification
The Pyridine,2,3-bis(chloromethyl)-, with the cas registry number 45754-12-9, has the systematic name of 2,3-bis(chloromethyl)pyridine.
The characteristics of this kind of chemical are as follows: (1)ACD/LogP: 1.76; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): 1; (4)ACD/LogD (pH 7.4): 1; (5)ACD/BCF (pH 5.5): 5; (6)ACD/BCF (pH 7.4): 5; (7)ACD/KOC (pH 5.5): 114; (8)ACD/KOC (pH 7.4): 115; (9)#H bond acceptors: 1; (10)#Freely Rotating Bonds: 2; (11)Polar Surface Area: 12.89; (12)Index of Refraction: 1.548; (13)Molar Refractivity: 43.875 cm3; (14)Molar Volume: 138.047 cm3; (15)Polarizability: 17.394 ×10-24 cm3; (16)Surface Tension: 42.237 dyne/cm; (17)Density: 1.275 g/cm3; (18)Flash Point: 139.294 °C; (19)Enthalpy of Vaporization: 48.21 kJ/mol; (20)Boiling Point: 264.48 °C at 760 mmHg; (21)Vapour Pressure: 0.016 mmHg at 25°C.
Additionally, the following datas could be converted into the molecular structure:
(1)SMILES:ClCc1ncccc1CCl
(2)InChI:InChI=1/C7H7Cl2N/c8-4-6-2-1-3-10-7(6)5-9/h1-3H,4-5H2
(3)InChIKey:FDHDTLFJPYRSBM-UHFFFAOYAK
What can I do for you?
Get Best Price
