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Cas Database |
| Name |
Riboxamide |
EINECS | N/A |
| CAS No. | 60084-10-8 | Density | 1.648g/cm3 |
| PSA | 154.14000 | LogP | -0.90370 |
| Solubility | N/A | Melting Point |
145-146° |
| Formula | C9H12 N2 O5 S | Boiling Point | 641.3°C at 760 mmHg |
| Molecular Weight | 260.271 | Flash Point | 341.6°C |
| Transport Information | N/A | Appearance | N/A |
| Safety | Moderately toxic by intravenous and intraperitoneal routes. Human systemic effects by intravenous route: headache, convulsions, and musculo-skeletal changes. Experimental reproductive effects. Mutation data reported. When heated to decomposition it emits toxic fumes of SOx and NOx. | Risk Codes | N/A |
| Molecular Structure |
|
Hazard Symbols | N/A |
| Synonyms |
2-b-D-Ribofuranosylthiazole-4-carboxamide;CI 909; NSC 286-193; NSC 286193; Riboxamide; TCAR; Tiazofurin; Tiazofurine |
Article Data | 12 |
Riboxamide Chemical Properties
IUPAC Name: 2-[3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]thiazole-4-carboxamide
Synonyms: 1,4-Anhydro-1-(4-carbamoyl-1,3-thiazol-2-yl)pentitol ; 2-((2R,4R,5R)-3,4-Dihydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-thiazole-4-carboxylic acid amide ; 2-(3,4-Dihydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-thiazole-4-carboxylic acid amide ; 2-(3,4-Dihydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-thiazole-4-carboxylic acid amide(tiazofurin) ; 2-[3,4-Dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,3-thiazole-4-carboxamide
CAS NO: 60084-10-8
Molecular Formula of Riboxamide (CAS NO.60084-10-8) : C9H12N2O5S
Molecular Weight of Riboxamide (CAS NO.60084-10-8) : 260.267
Molecular Structure of Riboxamide (CAS NO.60084-10-8) :.png)
Index of Refraction: 1.674
Surface Tension: 88.5 dyne/cm
Density: 1.648 g/cm3
Flash Point: 341.6 °C
Enthalpy of Vaporization: 99.49 kJ/mol
Boiling Point: 641.3 °C at 760 mmHg
Vapour Pressure: 2.53E-17 mmHg at 25°C
Riboxamide Toxicity Data With Reference
| 1. | dni-mus:lym 10 µmol/L | CNREA8 Cancer Research. 45 (1985),5512. | ||
| 2. | dni-mus:leu 10 µmol/L | BCPCA6 Biochemical Pharmacology. 34 (1985),1109. | ||
| 3. | ivn-hmn TDLo:1135 mg/kg/15D-I:CNS,MSK | CNREA8 Cancer Research. 45 (1985),5169. | ||
| 4. | ivn-hmn TDLo:892 mg/kg/10D-I:CNS | CNREA8 Cancer Research. 45 (1985),5169. | ||
| 5. | ipr-mus LD50:1684 mg/kg | NCISP* National Cancer Institute Screening Program Data Summary, Developmental Therapeutics Program, Bethesda, MD 20205 JAN86 . | ||
| 6. | ivn-mus LD50:3400 mg/kg | NTIS** National Technical Information Service. (Springfield, VA 22161) (Formerly U.S. Clearinghouse for Scientific and Technical Information) PB83-156901 . | ||
| 7. | ivn-dog LDLo:1090 mg/kg | NTIS** National Technical Information Service. (Springfield, VA 22161) (Formerly U.S. Clearinghouse for Scientific and Technical Information) PB83-156901 . |
Riboxamide Safety Profile
Moderately toxic by intravenous and intraperitoneal routes. Human systemic effects by intravenous route: headache, convulsions, and musculo-skeletal changes. Experimental reproductive effects. Mutation data reported. When heated to decomposition it emits toxic fumes of SOx and NOx.
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