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Sodium mersalyl

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Name

Sodium mersalyl

EINECS N/A
CAS No. 492-18-2 Density g/cm3
PSA 103.24000 LogP -0.22530
Solubility N/A Melting Point N/A
Formula C13H16HgNO6•Na Boiling Point °Cat760mmHg
Molecular Weight 505.88 Flash Point °C
Transport Information N/A Appearance N/A
Safety Poison by intravenous, intramuscular, and intraperitoneal routes. Used as a diuretic agent. When heated to decomposition it emits very toxic fumes of Hg, NOx, and Na2O. See also MERCURY COMPOUNDS, INORGANIC; MERCURY COMPOUNDS, ORGANIC. Risk Codes N/A
Molecular Structure Molecular Structure of 492-18-2 (mersalyl) Hazard Symbols N/A
Synonyms

Mercusal;Mercuramide;Diursal;Mercurital;Igrosin;Salyrgan;Mersalyl acid sodium salt;Sodium mersalyl;Mersalyl;

 

Sodium mersalyl Chemical Properties

IUPAC Name: Sodium[2-methoxy-3-[[2-(2-oxido-2-oxoethoxy)benzoyl]amino]propyl]mercuryhydrate
Molecular Formula: C13H16HgNO6•Na
Molecular Weight: 505.88g/mol
Freely Rotating Bonds: 10
Polar Surface Area: 107.92 Å2 
The Cas Register Number of Sodium mersalyl is 492-18-2 .The chemical synonyms of Sodium mersalyl (CAS No.492-18-2) are Acetic acid, (o-((3-(hydroxymercuri)-2-methoxypropyl)carbamoyl)phenoxy)-, monosodium salt ; (3-((2-(Carboxymethoxy)benzoyl)amino)-2-methoxypropyl)hydroxymercury monosodium salt ; Diursal ; 0-((3-Hydroxymercuri-2-methoxypropyl)carbamoyl)phenoxyacetic acid monosodium salt ; N-(Gamma-hydroxymercuri-beta-methoxypropyl)salicylamide-o-acetic acid sodium salt ; Igrosin ; Mercuramide ; Mercurital ; Mercury, (3-(0-(carboxymethoxy)benzamido)-2-methoxypropyl)hydroxy-, monosodium salt ; Mercusal ; Mersalil ; Mersalyl ; Mersalyl acid sodium salt ; Salurin ; Salyrgan ; Sodium o-((3-(hydroxymercuri)-2-methoxypropyl)carbamoyl)phenoxy acetate ; Sodium mersalyl ; Sodium salicyl-(gamma-hydroxymercuri-beta-methoxypropyl)amide-o-acetate ; Uragan .The molecular structure of Sodium mersalyl (CAS No.492-18-2) is.

Sodium mersalyl Uses

It is often used as a mercurial diuretic.

Sodium mersalyl Toxicity Data With Reference

1.    

ivn-rat LD50:17,700 µg/kg

    JAPMA8    Journal of the American Pharmaceutical Association, Scientific Edition. 40 (1951),249.
2.    

ims-rat LD50:24 mg/kg

    JAPMA8    Journal of the American Pharmaceutical Association, Scientific Edition. 40 (1951),249.
3.    

ipr-mus LD50:118 mg/kg

    JOCEAH    Journal of Organic Chemistry. 16 (1951),1879.
4.    

ivn-mus LD50:72,600 µg/kg

    JAPMA8    Journal of the American Pharmaceutical Association, Scientific Edition. 40 (1951),249.
5.    

ivn-rbt LDLo:7 mg/kg

    AEPPAE    Naunyn-Schmiedebergs Archiv fuer Experimentelle Pathologie und Pharmakologie. 152 (1930),341.
6.    

ims-rbt LD50:24 mg/kg

    JAPMA8    Journal of the American Pharmaceutical Association, Scientific Edition. 40 (1951),249.

Sodium mersalyl Consensus Reports

Mercury and its compounds are on the Community Right-To-Know List.

Sodium mersalyl Safety Profile

Poison by intravenous, intramuscular, and intraperitoneal routes. Used as a diuretic agent. When heated to decomposition it emits very toxic fumes of Hg, NOx, and Na2O. See also MERCURY COMPOUNDS, INORGANIC; MERCURY COMPOUNDS, ORGANIC.
HazardClass: 6.1 (a)
PackingGroup: II

Sodium mersalyl Standards and Recommendations

OSHA PEL: CL 0.1 mg(Hg)/m3 (skin)
ACGIH TLV: TWA 0.1 mg(Hg)/m3 (skin); BEI: 35 µg/g creatinine total inorganic mercury in urine preshift; 15 µg/g creatinine total inorganic mercury in blood at end of shift at end of workweek.
DFG MAK: Confirmed Animal Carcinogen with Unknown Relevance to Humans

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