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Cas Database

Name	Solvent Red 43	EINECS	239-138-3
CAS No.	15086-94-9	Density	1.02 g/mL at 20oC
PSA	93.40000	LogP	6.12210
Solubility	N/A	Melting Point	300 °C
Formula	C₂₀H₈Br₄O₅	Boiling Point	640.3 °C at 760 mmHg
Molecular Weight	647.897	Flash Point	341 °C
Transport Information	UN 1170 3/PG 2	Appearance	orange-brown powder
Safety	26	Risk Codes	36
Molecular Structure		Hazard Symbols	Xi
Synonyms	Fluorescein,2',4',5',7'-tetrabromo- (7CI,8CI);3,6-Dihydroxy-2,4,5,7-tetrabromospiro[xanthene-9,3'-phthalide];C.I. 45380:2;C.I. Solvent Red 43;D and C Red No. 21;C Red No. 21;Eosin Y spirit soluble;Eosin acid;Eosine acid;Japan Red 223;	Article Data	16

Solvent Red 43 Synthetic route

: 2321-07-5
fluorescein

: 15086-94-9
eosin y

Conditions

Conditions	Yield
With Oxone; sodium bromide at 200℃; for 12h;	100%
With sodium hypochlorite; hydrogen bromide; sodium sulfite In 2-methyltetrahydrofuran; water at 20℃; for 3h; Flow reactor;	78%
With ethanol; bromine

: 518-47-8
fluorescein disodium salt

: 15086-94-9
eosin y

Conditions

Conditions	Yield
With N-Bromosuccinimide In ethanol at 20℃; for 0.5h;	89%

: 85-44-9
phthalic anhydride

: 18011-67-1
2,4-dibromo-1,3-benzenediol

: 15086-94-9
eosin y

Conditions

Conditions	Yield
With zinc(II) chloride

: 3341-06-8
3,5-dibromo-2'-carboxy-2,4-dihydroxybenzophenone

: 5435-44-9, 22243-66-9
(E)-3-Ureido-but-2-enoic acid ethyl ester

A: 85-44-9
phthalic anhydride

B: 15086-94-9
eosin y

Conditions

Conditions	Yield
at 230 - 240℃;

: 3341-06-8
3,5-dibromo-2'-carboxy-2,4-dihydroxybenzophenone

A: 85-44-9
phthalic anhydride

B: 15086-94-9
eosin y

Conditions

Conditions	Yield
With zinc(II) chloride at 235 - 240℃; im Wasserstoffstrom;

: 596-28-1
3,3-bis-(3,4-dihydroxy-phenyl)-3H-isobenzofuran-1-one

: 3147-46-4
3,5-dibromo-4-hydroxysalicylic acid

: 5435-44-9, 22243-66-9
(E)-3-Ureido-but-2-enoic acid ethyl ester

: 15086-94-9
eosin y

Conditions

Conditions	Yield
at 170℃;

: 152-75-0
eosine

: 15086-94-9
eosin y

Conditions

Conditions	Yield
In 1,4-dioxane Equilibrium constant; Investigation of the effect of various organic solvents.;

: 518-47-8
fluorescein sodium salt

: 15086-94-9
eosin y

Conditions

Conditions	Yield
With potassium bromate; sulfuric acid; potassium bromide In water; acetone for 2h;	1.15 g

: 7664-93-9
sulfuric acid

: 26799-78-0
Eosin ethyl ester

: 15086-94-9
eosin y

Conditions

Conditions	Yield
at 150℃;

: 64-17-5
ethanol

: 2321-07-5
fluorescein

bromine (4 mol): bromine (4 mol)

: 15086-94-9
eosin y

Solvent Red 43 Chemical Properties

Molecular Structure of BROMEOSIN(15086-94-9):

IUPAC Name:2',4',5',7'-tetrabromo-3',6'-dihydroxyspiro[2-benzofuran-3,9'-xanthene]-1-one
Molecular Formula:C₂₀H₈Br₄O₅
Molecular Weight:647.890520 g/mol
Appearance:red-brown crystalline powder
Melting Point:300 °C
Density:2.5 g/cm³
Flash Point:341 °C
Enthalpy of Vaporization:97.98 kJ/mol
Boiling Point:640.3 °C at 760 mmHg
Vapour Pressure:5.42E-17 mmHg at 25 °C
EINECS:241-409-6
Synonyms of BROMEOSIN(15086-94-9):
BROMO ACID J;BROMO ACID J TS, XL, OR XX;BROMOFLUORESCEIN;BRONZE BROMO ES;EOSIN Y;EOSIN Y DISODIUM SALT;EOSIN YELLOWISH WATER-SOLUBLE;EOSIN YELLOWISH Y;Solvent Red 43
Categories of BROMEOSIN(15086-94-9):Organics

Solvent Red 43 Uses

BROMEOSIN(15086-94-9) is used as a biological stain.

Solvent Red 43 Toxicity Data With Reference

1.	dnr-bcs 2 mg/disc	TRENAF Kenkyu Nenpo-Tokyo-toritsu Eisei Kenkyusho. Annual Report of Tokyo Metropolitan Research Laboratory of Public Health. 27 (1976),153.
2.	scu-mus LDLo:450 mg/kg	HBAMAK “Abdernalden’s Handbuch der Biologischen Arbeitsmethoden.“ 4 (1935),1289.
3.	scu-frg LDLo:1 g/kg	HBAMAK “Abdernalden’s Handbuch der Biologischen Arbeitsmethoden.“ 4 (1935),1289.

Solvent Red 43 Consensus Reports

IARC Cancer Review: Group 3 IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 7 (1987),p. 56(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) , Animal Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 15 (1977),p. 183(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) . Reported in EPA TSCA Inventory.

Solvent Red 43 Safety Profile

The safety information of BROMEOSIN(15086-94-9) is as follows:
Hazard Codes:Xi

Risk Statements:36
36:Irritating to the eyes
Safety Statements:26
26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
RIDADR:UN 1170 3/PG 2
WGK Germany:3
RTECS:LM5850000
Mutation data reported. Incompatible with reducing agents. When heated to decomposition it emits very toxic fumes of Br⁻. See also BROMIDES.

Solvent Red 43 Specification

Storage information of BROMEOSIN(15086-94-9):
Store in a cool, dry place. Store in a tightly closed container.

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