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| Name |
Sulfosfamide |
EINECS | N/A |
| CAS No. | 37753-10-9 | Density | 1.41g/cm3 |
| PSA | 103.13000 | LogP | 2.03100 |
| Solubility | N/A | Melting Point |
N/A |
| Formula | C8H18 Cl N2 O5 P S | Boiling Point | 468.7°Cat760mmHg |
| Molecular Weight | 320.734 | Flash Point | 237.3°C |
| Transport Information | N/A | Appearance | N/A |
| Safety | Poison by intravenous and intraperitoneal routes. Mutation data reported. When heated to decomposition it emits very toxic fumes of POx, SOx, Cl−, and NOx. | Risk Codes | N/A |
| Molecular Structure |
|
Hazard Symbols | N/A |
| Synonyms |
Ethanol,2-[[3-(2-chloroethyl)tetrahydro-2-oxido-2H-1,3,2-oxazaphosphorin-2-yl]amino]-,methanesulfonate (ester) (9CI);Ethanol,2-[[3-(2-chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorin-2-yl]amino]-,methanesulfonate (ester), P-oxide;Asta 5122;Sufosfamide; |
Sulfosfamide Chemical Properties
IUPAC Name: 2-[[2-(2-Chloroethyl)-1-oxo-6-oxa-2-aza-1$l^{5}-phosphacyclohex-1-yl]amino]ethyl methanesulfonate
Molecular Formula: C8H18ClN2O5PS
Molecular Weight: 320.76
Freely Rotating Bonds: 6
Polar Surface Area: 94.34 Å2
Index of Refraction: 1.516
Molar Refractivity: 68.45 cm3
Molar Volume: 226.3 cm3
Polarizability: 27.13 ×10-24 cm3
Surface Tension: 51.3 dyne/cm
Density: 1.41 g/cm3
Flash Point: 237.3 °C
Enthalpy of Vaporization: 73.09 kJ/mol
Boiling Point: 468.7 °C at 760 mmHg
Vapour Pressure: 5.87E-09 mmHg at 25°C
The Cas Register Number of Sulfosfamide is 37753-10-9.The chemical synonyms of Sulfosfamide (CAS NO.37753-10-9) are 2-((3-(2-Chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorin-2-yl)amino)ethanol methanesulfonate (ester) P-oxide ; 3-(2-Chloroethyl)-2-(2-mesyloxyethylamino)tetrahydro-2H-1,3,2-oxazaphosphorin-2-oxide ; Ethanol, 2-((3-(2-chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorin-2-yl)amino)-, methanesulfonate (ester), P-oxide ; Sufosfamide ; Sufosfamidum .The molecular structure of Sulfosfamide (CAS NO.37753-10-9) is
.
Sulfosfamide Uses
Sulfosfamide (CAS NO.37753-10-9) is used as pharmaceutical intermediate .
Sulfosfamide Toxicity Data With Reference
| 1. | mnt-mus-ipr 160 mg/kg/24H | MUREAV Mutation Research. 56 (1978),319. | ||
| 2. | ipr-rat LD50:120 mg/kg | ARZNAD Arzneimittel-Forschung. Drug Research. 24 (1974),1149. | ||
| 3. | ivn-rat LD50:102 mg/kg | ARZNAD Arzneimittel-Forschung. Drug Research. 24 (1974),1149. | ||
| 4. | ipr-mus LD50:136 mg/kg | ARZNAD Arzneimittel-Forschung. Drug Research. 24 (1974),1149. | ||
| 5. | ivn-mus LD50:91 mg/kg | ARZNAD Arzneimittel-Forschung. Drug Research. 24 (1974),1149. |
Sulfosfamide Consensus Reports
EPA Genetic Toxicology Program.
Sulfosfamide Safety Profile
Poison by intravenous and intraperitoneal routes. Mutation data reported. When heated to decomposition it emits very toxic fumes of POx, SOx, Cl−, and NOx.
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