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Toceranib

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Name

Toceranib

EINECS N/A
CAS No. 356068-94-5 Density 1.293
PSA 77.23000 LogP 3.55570
Solubility N/A Melting Point N/A
Formula C22H25FN4O2 Boiling Point 596.8±50.0 °C(Predicted)
Molecular Weight 396.46 Flash Point N/A
Transport Information N/A Appearance N/A
Safety Risk Codes N/A
Molecular Structure Molecular Structure of 356068-94-5 (Toceranib) Hazard Symbols N/A
Synonyms

PHA-291639;Toceranib [USAN];UNII-59L7Y0530C;5-[(Z)-(5-fluoro-2-oxo-1H-indol-3-ylidene)methyl]-2,4-dimethyl-N-(2-pyrrolidin-1-ylethyl)-1H-pyrrole-3-carboxamide;

 

Toceranib Specification

The Toceranib, with the CAS registry number 356068-94-5, is also known as PHA-291639. This chemical's molecular formula is C22H25FN4O2 and molecular weight is 396.46. What's more, its IUPAC name is 5-[(Z)-(5-fluoro-2-oxo-1H-indol-3-ylidene)methyl]-2,4-dimethyl-N-(2-pyrrolidin-1-ylethyl)-1H-pyrrole-3-carboxamide. Its classification code is Treatment of mast cell tumors in dogs. Toceranib is a receptor tyrosine kinase inhibitor and is used in the treatment of canine mast cell tumor also called mastocytoma. It is likely to act mostly through inhibition of the kit tyrosine kinase, though it may also have an anti-angiogenic effect.

You can still convert the following datas into molecular structure:
(1)Canonical SMILES: CC1=C(NC(=C1C(=O)NCCN2CCCC2)C)C=C3C4=C(C=CC(=C4)F)NC3=O
(2)Isomeric SMILES: CC1=C(NC(=C1C(=O)NCCN2CCCC2)C)/C=C\3/C4=C(C=CC(=C4)F)NC3=O
(3)InChI: InChI=1S/C22H25FN4O2/c1-13-19(12-17-16-11-15(23)5-6-18(16)26-21(17)28)25-14(2)20(13)22(29)24-7-10-27-8-3-4-9-27/h5-6,11-12,25H,3-4,7-10H2,1-2H3,(H,24,29)(H,26,28)/b17-12-
(4)InChIKey: SRSGVKWWVXWSJT-ATVHPVEESA-N

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