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Trimethylmethoxysilane

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Name

Trimethylmethoxysilane

EINECS 217-369-0
CAS No. 1825-61-2 Density 0.762 g/cm3
PSA 9.23000 LogP 1.46770
Solubility N/A Melting Point N/A
Formula C4H12OSi Boiling Point 57.5 °C at 760 mmHg
Molecular Weight 104.224 Flash Point -11°C
Transport Information UN 1993 3/PG 2 Appearance Clear colorless liquid
Safety 16-26 Risk Codes 11-36
Molecular Structure Molecular Structure of 1825-61-2 (METHOXYTRIMETHYLSILANE) Hazard Symbols IrritantXi, FlammableF
Synonyms

LS 510;Methoxytrimethylsilane;Methyl trimethylsilyl ether;NSC 139858;SS 2010;TSL8111;Trimethylsilyl methyl ether;Z 6013;

Article Data 183

Trimethylmethoxysilane Synthetic route

13368-42-8

4-(trimethylsilyl)morpholine

2623-87-2

bromobutyric acid

A

1825-61-2

Methoxytrimethylsilane

B

6377-82-8

morpholinium hydrobromide

C

trimethylsilyl 4-morpholinobutyrate

Conditions
ConditionsYield
With methanol at 20℃; for 24h;A n/a
B 99.1%
C 71%
67-56-1

methanol

82340-08-7, 82340-09-8

1,2-Diphenyl-1,2-bis<1-(trimethylsiloxy)ethenyl>diphosphan

A

1825-61-2

Methoxytrimethylsilane

B

79-20-9

acetic acid methyl ester

C

34478-62-1

1,2-diphenyldiphosphane

Conditions
ConditionsYield
for 1h; Product distribution; Ambient temperature;A n/a
B n/a
C 99%
80631-66-9

1-cyclopropyl-1-methoxytetramethyldisilane

A

1825-61-2

Methoxytrimethylsilane

B

22053-38-9

1,3-dimethyl-1,3-divinyl-1,3-disilacyclobutane

Conditions
ConditionsYield
at 680℃; under 4E-05 Torr;A 99%
B 42%
67-56-1

methanol

91482-61-0

2,5-dimethyl-4-acetyl-5-trimethylsiloxy-1,3,4-oxadiazoline-2

A

1825-61-2

Methoxytrimethylsilane

B

91482-60-9

trisacetylhydrazine

Conditions
ConditionsYield
In dichloromethane at 24℃; for 0.5h; Product distribution;A n/a
B 98%
18243-41-9

(bromomethyl)trimethylsilane

124-41-4

sodium methylate

A

1825-61-2

Methoxytrimethylsilane

B

14704-14-4

(methoxymethyl)trimethylsilane

Conditions
ConditionsYield
In methanol for 19h; Heating;A 0.5%
B 98%
107-46-0

Hexamethyldisiloxane

616-38-6

carbonic acid dimethyl ester

1825-61-2

Methoxytrimethylsilane

Conditions
ConditionsYield
With methanol; aluminum oxide; potassium fluoride at 400℃;98%
4656-04-6

bis(trimethylsilyl)mercury

1067-52-3

tributyltin methoxide

A

1825-61-2

Methoxytrimethylsilane

B

813-19-4

bis(tri-n-butyltin)

C

mercury

Conditions
ConditionsYield
In benzene 25°C; 0.1 h;A 95%
B 98%
C 96%
67-56-1

methanol

80395-65-9

(2-Trimethylsilanyl-1-trimethylsilanyloxy-cyclopropyl)-phosphonic acid diethyl ester

A

1825-61-2

Methoxytrimethylsilane

B

80406-85-5

diethyl <1-hydroxy-2-(trimethylsilyl)cyclopropyl>phosphonate

Conditions
ConditionsYield
for 120h; Ambient temperature;A 97%
B 85%
80395-65-9

(2-Trimethylsilanyl-1-trimethylsilanyloxy-cyclopropyl)-phosphonic acid diethyl ester

A

1825-61-2

Methoxytrimethylsilane

B

80406-85-5

diethyl <1-hydroxy-2-(trimethylsilyl)cyclopropyl>phosphonate

Conditions
ConditionsYield
With methanol for 120h; Ambient temperature;A 97%
B 85%
7677-24-9

trimethylsilyl cyanide

potassium (pentafluoroethyl)trimethoxyborate

A

1825-61-2

Methoxytrimethylsilane

B

potassium cyano-dimethoxypentafluoroethylborate

Conditions
ConditionsYield
In tetrahydrofuran at 20℃; for 4h; Inert atmosphere;A n/a
B 97%

Trimethylmethoxysilane Specification

The Silane,methoxytrimethyl-, with the CAS registry number 1825-61-2 and EINECS registry number 217-369-0, has the systematic name of methoxy(trimethyl)silane. It is a kind of clear colorless liquid, and belongs to the following product categories: Monoalkoxysilanes; Si (Classes of Silicon Compounds); Si-O Compounds. And the molecular formula of the chemical is C4H12OSi.

The characteristics of Silane,methoxytrimethyl- are as followings: (1)ACD/LogP: 1.62; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): 1.62; (4)ACD/LogD (pH 7.4): 1.62; (5)ACD/BCF (pH 5.5): 10.01; (6)ACD/BCF (pH 7.4): 10.01; (7)ACD/KOC (pH 5.5): 181.02; (8)ACD/KOC (pH 7.4): 181.02; (9)#H bond acceptors: 1; (10)#H bond donors: 0; (11)#Freely Rotating Bonds: 1; (12)Polar Surface Area: 9.23 Å2; (13)Index of Refraction: 1.371; (14)Molar Refractivity: 31.04 cm3; (15)Molar Volume: 136.6 cm3; (16)Polarizability: 12.3×10-24cm3; (17)Surface Tension: 15.2 dyne/cm; (18)Density: 0.762 g/cm3; (19)Enthalpy of Vaporization: 28.78 kJ/mol; (20)Boiling Point: 57.5 °C at 760 mmHg; (21)Vapour Pressure: 230 mmHg at 25°C.

Preparation of Silane,methoxytrimethyl-: This chemical can be prepared by methanol and chloro-trimethyl-silane. The reaction will need reagent pyridine and toluene. 

Uses of Silane,methoxytrimethyl-: It can react with vinylbenzene to produce 2-fluoro-1-methoxy-1-phenylethane. This reaction will need reagent N-fluoropentachloropyridinium triflate. The reaction time is 5 days with ambient temperature, and the yield is about 54%.

You should be cautious while dealing with this chemical. It is a kind of flammable chemical which irritates to eyes. Therefore, you had better take the following instructions: Keep away from sources of ignition, and if in case of contacting with eyes, rinse immediately with plenty of water and seek medical advice.

Addtionally, the following datas could be converted into the molecular structure:
(1)SMILES: O(C)[Si](C)(C)C
(2)InChI: InChI=1/C4H12OSi/c1-5-6(2,3)4/h1-4H3
(3)InChIKey: POPACFLNWGUDSR-UHFFFAOYAM

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