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Name |
Vinburnine |
EINECS | 225-490-5 |
CAS No. | 4880-88-0 | Density | 1.34 g/cm3 |
PSA | 25.24000 | LogP | 3.71250 |
Solubility | N/A | Melting Point |
174-177 °C(lit.) |
Formula | C19H22N2O | Boiling Point | 441.9 °C at 760 mmHg |
Molecular Weight | 294.396 | Flash Point | 221 °C |
Transport Information | N/A | Appearance | White to slightly yellow crystalline powder |
Safety | 22-24/25 | Risk Codes | N/A |
Molecular Structure | Hazard Symbols | N/A | |
Synonyms |
Vincamone(7CI,8CI);(-)-Eburnamonine;(-)-Vincamone;(-)-cis-Eburnamonine;(3a,16a)-Eburnamonine;16-Oxoeburnane;CH 846;Cervoxan;Eburnal Ritardo;Vinburnine;cis-Vincamone;l-Eburnamonine; |
Article Data | 40 |
The CAS register number of Eburnamenin-14(15H)-one,(3a,16a)- is 4880-88-0. It also can be called as l-Eburnamonine and the systematic name about this chemical is (3α,16α)-14,15-dihydroeburnamenin-14-one. The molecular formula about this chemical is C19H22N2O and the molecular weight is 294.39. It belongs to the following product categories which include Alkaloids; Complex Molecules; Asymmetric Synthesis; Chiral Building Blocks and so on.
Physical properties about Eburnamenin-14(15H)-one,(3a,16a)- are: (1)ACD/LogP: 3.79; (2)ACD/LogD (pH 5.5): 1.27; (3)ACD/LogD (pH 7.4): 2.97; (4)ACD/BCF (pH 5.5): 1.36; (5)ACD/BCF (pH 7.4): 68.52; (6)ACD/KOC (pH 5.5): 8.4; (7)ACD/KOC (pH 7.4): 421.86; (8)#H bond acceptors: 3; (9)#Freely Rotating Bonds: 1; (10)Polar Surface Area: 25.24 Å2; (11)Index of Refraction: 1.718; (12)Molar Refractivity: 86.47 cm3; (13)Molar Volume: 219.2 cm3; (14)Polarizability: 34.28x10-24cm3; (15)Surface Tension: 54.3 dyne/cm; (16)Density: 1.34 g/cm3; (17)Flash Point: 221 °C; (18)Enthalpy of Vaporization: 69.93 kJ/mol; (19)Boiling Point: 441.9 °C at 760 mmHg; (20)Vapour Pressure: 5.25E-08 mmHg at 25 °C.
When you are using this chemical, please be cautious about it as the following:
When you are using this chemical, do not breathe dust and avoid contact with skin and eyes. It is stable under normal temperature and pressure. If you want to store it, avoid contact with strong oxidant and keep the container tightly sealed in dry, cool places.
You can still convert the following datas into molecular structure:
(1)SMILES: O=C5n1c3c(c2ccccc12)CCN4[C@H]3[C@](CCC4)(CC)C5
(2)InChI: InChI=1/C19H22N2O/c1-2-19-9-5-10-20-11-8-14-13-6-3-4-7-15(13)21(16(22)12-19)17(14)18(19)20/h3-4,6-7,18H,2,5,8-12H2,1H3/t18-,19+/m1/s1
(3)InChIKey: WYJAPUKIYAZSEM-MOPGFXCFBD
(4)Std. InChI: InChI=1S/C19H22N2O/c1-2-19-9-5-10-20-11-8-14-13-6-3-4-7-15(13)21(16(22)12-19)17(14)18(19)20/h3-4,6-7,18H,2,5,8-12H2,1H3/t18-,19+/m1/s1
(5)Std. InChIKey: WYJAPUKIYAZSEM-MOPGFXCFSA-N
The toxicity data are as follows:
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
mouse | LD50 | intraperitoneal | 265mg/kg (265mg/kg) | SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS | Medicamentos de Actualidad. Vol. 14, Pg. 160, 1978. |
mouse | LD50 | intravenous | 28mg/kg (28mg/kg) | SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD | Medicamentos de Actualidad. Vol. 14, Pg. 160, 1978. |
mouse | LD50 | oral | 3gm/kg (3000mg/kg) | United States Patent Document. Vol. #3852453, |