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10453-86-8

Basic Information
CAS No.: 10453-86-8
Name: RESMETHRIN
Article Data: 2
Molecular Structure:
Molecular Structure of 10453-86-8 (RESMETHRIN)
Formula: C22H26 O3
Molecular Weight: 338.447
Synonyms: Cyclopropanecarboxylicacid, 2,2-dimethyl-3-(2-methyl-1-propenyl)-, [5-(phenylmethyl)-3-furanyl]methylester (9CI); Cyclopropanecarboxylic acid, 2,2-dimethyl-3-(2-methylpropenyl)-,(5-benzyl-3-furyl)methyl ester (8CI); 3-Furanmethanol, 5-benzyl-,2,2-dimethyl-3-(2-methylpropenyl)cyclopropanecarboxylate (8CI);(5-Benzyl-3-furyl)methyl2,2-dimethyl-3-(2-methylpropenyl)cyclopropanecarboxylate;(5-Benzyl-3-furyl)methyl chrysanthemate; (5-Benzyl-3-furyl)methyl-DL-cis,trans-chrysanthemate; 5-Benzyl-3-furylmethyl (?à)-cis-trans-chrysanthemate; 5-Benzylfurfuryl chrysanthemate;ARI-B; Chrysron; Crossfire; Enforcer; NIA 17370; NRDC 104; Penick 1382;Penncapthrin; Pyresthrin; Resmethrin; SBP 1382; SBP 1383; Seco;[5-(Phenylmethyl)-3-furanyl]methyl2,2-dimethyl-3-(2-methyl-1-propenyl)cyclopropanecarboxylate; dl-cis,trans-[(5-Benzyl-3-furyl)methyl]chrysanthemumate
Density: 1.111g/cm3
Melting Point: 56.5℃
Boiling Point: 418.3oC at 760 mmHg
Flash Point: 206.8oC
Solubility: 0.038 mg l-1 (25 °C)
Hazard Symbols: Xn,N
Risk Codes: 22-50/53
Safety: Poison by ingestion, and intravenous routes. Moderately toxic by inhalation and skin contact. When heated to decomposition it emits acrid and irritating fumes. See also ESTERS.
PSA: 39.44000
LogP: 5.15200
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Chemistry

Product Name: Resmethrin (CAS NO.10453-86-8)


Molecular Formula: C22H26O3
Molecular Weight: 338.44g/mol
Mol File: 10453-86-8 .mol
Einecs: 233-940-7
Appearance: Colorless crystals or waxy solid
Boiling point: 415.6 °C at 760 mmHg
Storage Temperature: 0-6°C
Flash Point: 205.2 °C
Density: 1.111 g/cm3
Water Solubility: Insoluble in water
Surface Tension: 43.9 dyne/cm
Enthalpy of Vaporization: 66.87 kJ/mol
Vapour Pressure: 4.07E-07 mmHg at 25°C
XLogP3-AA: 6.1
H-Bond Donor: 0
H-Bond Acceptor: 3
Product Categories: PyrethroidsAnalytical Standards; Alphabetic; Endocrine Disruptors (Draft)Pesticides; EPA; Insecticides; Method Specific; R; Alpha sort; PyrethroidsPesticides&Metabolites; Q-ZAnalytical Standards

Uses

 Resmethrin (CAS NO.10453-86-8) has a strong contact action, pesticides are very efficient, the virulence of the housefly is 2.5 times higher than the pyrethrins; its virulence mosquito Culex pipiens than allethrin is about three times higher; it Blattella germanica poison force, more than tetramethrin is about 6 times higher. And its mammalian toxicity, lower than the pyrethrins. It is suitable for families, housing, warehouses and other sites of mosquitoes, flies, cockroaches and other pests prevention and treatment.

Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
bird - wild LD50 oral 75mg/kg (75mg/kg)   Archives of Environmental Contamination and Toxicology. Vol. 12, Pg. 355, 1983.
dog LC inhalation > 420mg/m3/4H (420mg/m3)   National Technical Information Service. Vol. AD747-345,
dog LDLo intravenous 250mg/kg (250mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: ATAXIA

GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS
National Technical Information Service. Vol. AD747-345,
mammal (species unspecified) LD50 intraperitoneal > 1gm/kg (1000mg/kg)   Oyo Yakuri. Pharmacometrics. Vol. 3, Pg. 325, 1969.
mammal (species unspecified) LD50 oral > 3375mg/kg (3375mg/kg)   Oyo Yakuri. Pharmacometrics. Vol. 3, Pg. 325, 1969.
mouse LD50 intraperitoneal > 1gm/kg (1000mg/kg) PERIPHERAL NERVE AND SENSATION: SENSORY CHANGE INVOLVING PERIPHERAL NERVE

BEHAVIORAL: TREMOR

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Oyo Yakuri. Pharmacometrics. Vol. 3, Pg. 325, 1969.
mouse LD50 oral 300mg/kg (300mg/kg)   Agricultural and Biological Chemistry. Vol. 37, Pg. 2681, 1973.
mouse LD50 skin > 5gm/kg (5000mg/kg)   Bochu Kagaku. Scientific Pest Control. Vol. 34, Pg. 157, 1969.
mouse LD50 subcutaneous > 2gm/kg (2000mg/kg)   Bochu Kagaku. Scientific Pest Control. Vol. 34, Pg. 157, 1969.
rabbit LD50 skin 2500mg/kg (2500mg/kg)   Special Publication of the Entomological Society of America. Vol. 78-1, Pg. 9, 1978.
rabbit LDLo intravenous 250mg/kg (250mg/kg) BEHAVIORAL: TREMOR

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: IRRITABILITY
National Technical Information Service. Vol. AD747-345,
rat LC inhalation > 420mg/m3/4H (420mg/m3)   National Technical Information Service. Vol. AD747-345,
rat LD50 oral 1244mg/kg (1244mg/kg)   Fundamental and Applied Toxicology. Vol. 7, Pg. 299, 1986.
rat LD50 skin 3gm/kg (3000mg/kg)   Yakkyoku. Pharmacy. Vol. 38, Pg. 1331, 1987.
rat LD50 subcutaneous > 5gm/kg (5000mg/kg)   Bochu Kagaku. Scientific Pest Control. Vol. 34, Pg. 157, 1969.
rat LDLo intraperitoneal 19200mg/kg (19200mg/kg)   National Technical Information Service. Vol. AD747-345,
rat LDLo intravenous 160mg/kg (160mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: ATAXIA

LUNGS, THORAX, OR RESPIRATION: ACUTE PULMONARY EDEMA
Biologico. Vol. 41, Pg. 283, 1975.

Consensus Reports

EPA FIFRA 1988 pesticide subject to registration or re-registration. EPA Genetic Toxicology Program.

Safety Profile

Poison by ingestion, and intravenous routes. Moderately toxic by inhalation and skin contact. When heated to decomposition it emits acrid and irritating fumes. See also ESTERS.
Safety Information of Resmethrin (CAS NO.10453-86-8):
Hazard Codes: XnHarmful,NDangerous
Risk Statements: 22-50/53 
22:  Harmful if swallowed
50:  Very Toxic to aquatic organisms
53:  May cause long-term adverse effects in the aquatic environment
Safety Statements: 60/61-61-60
60:  This material and/or its container must be disposed of as hazardous waste 
61:  Avoid release to the environment. Refer to special instructions safety data sheet 

Specification

 Resmethrin ,its CAS NO. is 10453-86-8 ,the synonyms is (5-(Phenylmethyl)-3-furanyl)methyl2,2-dimethyl-3-(2-methyl-1-propenyl)cyclop ; (5-(Phenylmethyl)-3-furanyl)methyl2,2-dimethyl-3-furylmethyl2,2-dimethyl-3)-2 ; (5-(Phenylmethyl)-3-furanyl)methylester ; (5-Benzyl-3-furyl)methyl 2,2-dimethyl-3-(2-methyl-1-propenyl)cyclopropanecarboxylate ; (5-Benzyl-3-furyl)methyl chrysanthemate ; (5-Benzyl-3-furyl)methyl(1rs)-cis,trans-2,2-dimethyl-3-(2-methylpropenyl)cyc ; (5-Benzyl-3-furyl)methyl-2,2-dimethyl-3-(2-methylpropenyl)-cyclopropanecarbo ; (5-Benzyl-3-furyl)methyl-2,2-dimethyl-3-(2-methylpropenyl)-cyclopropanecarboxy .