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14148-99-3

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Basic Information
CAS No.: 14148-99-3
Name: Lefetamine hydrochloride
Molecular Structure:
Molecular Structure of 14148-99-3 (Lefetamine hydrochloride)
Formula: C16H19 N . Cl H
Molecular Weight: 261.82
Synonyms: Benzeneethanamine,N,N-dimethyl-a-phenyl-,hydrochloride, (R)-; Ethylamine, N,N-dimethyl-1,2-diphenyl-, hydrochloride,(R)(-)- (8CI); Lefetamine hydrochloride; SPA; SPA (analgesic)
Melting Point: 218-219°
Safety: Poison by ingestion, intravenous, and subcutaneous routes. When heated to decomposition it emits very toxic fumes of HCl and NOx.
PSA: 3.24000
LogP: 4.33400
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  • 1,2-diphenylethyl(dimethyl)azanium chloride

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    1,2-diphenylethyl(dimethyl)azanium chloride

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Chemistry

IUPAC  Name: 1,2-Diphenylethyl(dimethyl)azanium chloride   
Molecular Formula: C16H19N•ClH
Molecular Weight: 261.82
Freely Rotating Bonds: 4
Polar Surface Area: 3.24 Å2
Index of Refraction: 1.568
Molar Refractivity: 73.27 cm3
Molar Volume: 223.9 cm3
Polarizability: 29.05 ×10-24 cm3
Surface Tension: 39 dyne/cm
Density: 1.006 g/cm3
Flash Point: 121 °C
Enthalpy of Vaporization: 53.52 kJ/mol
Boiling Point: 295.5 °C at 760 mmHg
Vapour Pressure: 0.00152 mmHg at 25°C 
The Cas Register Number of 1,2-Diphenyl-1-(dimethylamino)ethane is 14148-99-3 .The chemical synonyms of 1,2-Diphenyl-1-(dimethylamino)ethane (CAS NO.14148-99-3) are Benzeneethanamine, N,N-dimethyl-alpha-phenyl-, (R)- ; Lefetamine .The molecular structure of 1,2-Diphenyl-1-(dimethylamino)ethane (CAS NO.14148-99-3) is.

Uses

 1,2-Diphenyl-1-(dimethylamino)ethane (CAS NO.14148-99-3) is used as organic intermediate .

Toxicity Data With Reference

1.    

orl-rat LD50:300 mg/kg

     DRFUD4    Drugs of the Future. 2 (1977),39.
2.    

scu-rat LD50:148 mg/kg

     AIPTAK    Archives Internationales de Pharmacodynamie et de Therapie. 221 (1976),105.
3.    

orl-mus LD50:176 mg/kg

     DRFUD4    Drugs of the Future. 2 (1977),39.
4.    

scu-mus LD50:104 mg/kg

     DRFUD4    Drugs of the Future. 2 (1977),39.
5.    

ivn-mus LD50:32,600 µg/kg

     DRFUD4    Drugs of the Future. 2 (1977),39.

Safety Profile

Poison by ingestion, intravenous, and subcutaneous routes. When heated to decomposition it emits very toxic fumes of HCl and NOx.