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CAS No.: | 171485-39-5 |
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Name: | (aR)-alpha-[(1S)-1-[2,6-Dimethoxy-4-(2-propen-1-yl)phenoxy]ethyl]-4-hydroxy-3-methoxybenzenemethanol |
Article Data: | 2 |
Molecular Structure: | |
Formula: | C21H26O6 |
Molecular Weight: | 374.434 |
Synonyms: | Benzenemethanol,a-[1-[2,6-dimethoxy-4-(2-propenyl)phenoxy]ethyl]-4-hydroxy-3-methoxy-,[S-(R*,S*)]-;Myrislignan; |
Density: | 1.167 g/cm3 |
Boiling Point: | 537.6±50.0 °C(Predicted) |
PSA: | 77.38000 |
LogP: | 3.64740 |
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The Myrislignan , its cas register number is 171485-39-5. It also can be called as (aR)-alpha-[(1S)-1-[2,6-Dimethoxy-4-(2-propen-1-yl)phenoxy]ethyl]-4-hydroxy-3-methoxybenzenemethanol and Benzenemethanol,a-[(1S)-1-[2,6-dimethoxy-4-(2-propen-1-yl)phenoxy]ethyl]-4-hydroxy-3-methoxy-,(aR)- .
In vitro metabolism of myrislignan in the seeds of Myristica fragrans, the objective is to study the metabolism of myrislignan isolated from the seed of Myristica fragrans Houtt.using in vitro drug-metabolizing enzymes prepared from the phenobarbital-induced rat liver microsomes, and to establish a method to cosmically prepare metabolites of myrislignan. And the methods about this examination is after incubation of myrislignan with drug-metabolizing enzymes prepared from the phenobarbital-induced rat liver microsomes at 37 °C in vitro,the high-performance liquid chromatography(HPLC) method was applied to analyze myrislignan and its metabolites. Also every study has a results, the results about this study is Myrislignan was metabolized by drug-metabolizing enzymes in rat liver microsomes to produce 7 metabolites.Conclusion: The established drug-metabolizing enzyme model is valid to study the metabolism of myrislignan in vitro.