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CAS No.: | 17901-01-8 |
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Name: | Boc-L-isoleucine methyl ester |
Article Data: | 18 |
Molecular Structure: | |
Formula: | C12H23NO4 |
Molecular Weight: | 245.319 |
Synonyms: | Isoleucine,N-carboxy-, N-tert-butyl methyl ester, L- (8CI);N-(tert-Butoxycarbonyl)isoleucine methyl ester;N-tert-Butoxycarbonyl-L-isoleucine methyl ester; |
PSA: | 64.63000 |
LogP: | 2.48970 |
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The L-Isoleucine,N-[(1,1-dimethylethoxy)carbonyl]-, methyl ester, with the CAS registry number 17901-01-8, is also known as N-tert-Butoxycarbonyl-L-isoleucine methyl ester and tert-Butyloxycarbonylisoleucine methyl ester. What's more, this chemical's molecular formula is C12H23NO4 and molecular weight is 245.3.
Preparation of L-Isoleucine,N-[(1,1-dimethylethoxy)carbonyl]-, methyl ester: this chemical is prepared by reaction of Diazomethane with N-tert-Butoxycarbonyl-L-isoleucine.
This reaction needs reagent Methanol, Diethyl ether at temperature of 4 °C. The yield is 98.5 %.
Uses of L-Isoleucine,N-[(1,1-dimethylethoxy)carbonyl]-, methyl ester: it is used to produce other chemicals. For example, it is used to produce Boc-L-Ile-ol.
The reaction occurs with reagent Sodium borohydride, Acetic acid and solvent Dioxane at temperature of 80 °C. The yield is 86 %.