Welcome to LookChem.com Sign In|Join Free
  • or
Home > Pharmaceutical > 182699 > 

182699-77-0

Basic Information
CAS No.: 182699-77-0
Name: 3A,4,5,7A-TETRAHYDRO-3,6-DIMETHYLBENZOFURAN-2(3H)-ONE
Article Data: 8
Molecular Structure:
Molecular Structure of 182699-77-0 (3A,4,5,7A-TETRAHYDRO-3,6-DIMETHYLBENZOFURAN-2(3H)-ONE)
Formula: C10H14 O2
Molecular Weight: 166.22
Synonyms: 2(3H)-Benzofuranone,3a,4,5,7a-tetrahydro-3,6-dimethyl-, [3S-(3a,3aa,7aa)]-; (-)-(3S,3aS,7aR)-Winelactone; (-)-Wine lactone; Wine lactone
Density: 1.042 g/cm3
Boiling Point: 286.3 ºC at 760 mmHg
Flash Point: 115.5 ºC
PSA: 26.30000
LogP: 1.90420
Synthetic route
477717-60-5

(3aS,7aS)-6-methyl-3-methylene-3a,4,5,7a-tetrahydrobenzofuran-2(3H)-one

A

182699-77-0

(-)-(3aS,3aS,7aR)-3a,4,5,7a-tetrahydro-3,6-dimethylbenzofuran-2(3H)-one

B

182699-79-2

(+)-(3aR,3aS,7aR)-3a,4,5,7a-tetrahydro-3,6-dimethylbenzofuran-2(3H)-one

Conditions
ConditionsYield
With [NH2Me2][{RuCl((S)-segphos)}2(μ-Cl)3]; hydrogen In 1,4-dioxane at 40℃; under 15001.5 Torr; for 6h; Inert atmosphere; Autoclave; diastereoselective reaction;A n/a
B 99%
With [NH2Me2][{RuCl((R)-H8-binap)}2(μ-Cl)3]; hydrogen In 1,4-dioxane at 30℃; under 15001.5 Torr; for 16h; Inert atmosphere; Autoclave; diastereoselective reaction;A 69%
B n/a
With sodium tetrahydroborate In ethanol at 20℃; for 1.5h; Product distribution; Further Variations:; Reagents;A 5 % Chromat.
B 92 % Chromat.
With magnesium In methanol at 20℃; for 3h;
263163-03-7

(+)-(3aS,7aR)-2,3,3a,4,5,7a-hexahydro-6-methylbenzofuran-2(3H)-one

74-88-4

methyl iodide

182699-77-0

(-)-(3aS,3aS,7aR)-3a,4,5,7a-tetrahydro-3,6-dimethylbenzofuran-2(3H)-one

Conditions
ConditionsYield
Stage #1: (+)-(3aS,7aR)-2,3,3a,4,5,7a-hexahydro-6-methylbenzofuran-2(3H)-one With n-butyllithium; diisopropylamine In tetrahydrofuran at -20 - 0℃; for 1h; Inert atmosphere;
Stage #2: methyl iodide With 1,3-dimethyl-2-imidazolidinone In tetrahydrofuran at 0 - 20℃; for 5h; Inert atmosphere;
90%
With lithium diisopropyl amide In tetrahydrofuran at -78℃; for 1.5h; Alkylation;79%
416864-79-4

(3S,3aS,6R,7R,7aR)-(3a,4,5,6,7,7a)-hexahydro-3,6-dimethylbenzofuran-2(3H)-one

182699-77-0

(-)-(3aS,3aS,7aR)-3a,4,5,7a-tetrahydro-3,6-dimethylbenzofuran-2(3H)-one

Conditions
ConditionsYield
With 1,8-diazabicyclo[5.4.0]undec-7-ene In tetrahydrofuran at 20℃; for 5h;76%
287720-48-3

(2RS)-2-<(1R)-4-methylcyclohex-3-enyl>propanoic acid

A

182699-77-0

(-)-(3aS,3aS,7aR)-3a,4,5,7a-tetrahydro-3,6-dimethylbenzofuran-2(3H)-one

B

182699-79-2

(+)-(3aR,3aS,7aR)-3a,4,5,7a-tetrahydro-3,6-dimethylbenzofuran-2(3H)-one

Conditions
ConditionsYield
With tert.-butylhydroperoxide; dipyridinium dichromate; Celite In N,N-dimethyl-formamide at 30℃; for 12h;
With tert.-butylhydroperoxide; dipyridinium dichromate; Celite In benzene at 30℃; for 12h;
182699-81-6

(3S,3aS,7aS)-3a,4,5,7a-tetrahydro-3,6-dimethylbenzofuran-2(3H)-one

182699-77-0

(-)-(3aS,3aS,7aR)-3a,4,5,7a-tetrahydro-3,6-dimethylbenzofuran-2(3H)-one

Conditions
ConditionsYield
With hydrogenchloride; sodium hydroxide 1.) water/MeOH, 80 deg C, 2 h, 2.) water/MeOH, 80 deg C, 2 h; Yield given. Multistep reaction;
182699-83-8

(3R,3aS,7aS)-3,6-dimethyl-3,3a,4,5-tetrahydrobenzofuran-2(7aH)-one

182699-77-0

(-)-(3aS,3aS,7aR)-3a,4,5,7a-tetrahydro-3,6-dimethylbenzofuran-2(3H)-one

Conditions
ConditionsYield
With hydrogenchloride; sodium hydroxide 1.) water/MeOH, 80 deg C, 2 h, 2.) water/MeOH, 80 deg C, 2 h; Yield given. Multistep reaction;
416864-77-2

2-((1R,4R)-4-Methyl-cyclohex-2-enyl)-propionic acid

182699-77-0

(-)-(3aS,3aS,7aR)-3a,4,5,7a-tetrahydro-3,6-dimethylbenzofuran-2(3H)-one

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: FeCl3; NaI / acetonitrile / 2.5 h / Heating
2: 76 percent / DBU / tetrahydrofuran / 5 h / 20 °C
View Scheme
160224-76-0

(-)-(3aS,7R,7aR)-hexahydro-7-iodo-benzo[b]furan-2-one

182699-77-0

(-)-(3aS,3aS,7aR)-3a,4,5,7a-tetrahydro-3,6-dimethylbenzofuran-2(3H)-one

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1: 82 percent / DBU / tetrahydrofuran / 3 h / Heating
2: 87 percent / CuBr*Me2S / tetrahydrofuran / 12 h / -10 °C
3: 60 percent / KI; I2; NaHCO3 / tetrahydrofuran; H2O / 2 h / 20 °C
4: 92 percent / DBU / tetrahydrofuran / 2 h / Heating
5: 79 percent / LDA / tetrahydrofuran / 1.5 h / -78 °C
View Scheme
263163-00-4

methyl (+)-(S)-(cyclohex-2-enyl)acetate

182699-77-0

(-)-(3aS,3aS,7aR)-3a,4,5,7a-tetrahydro-3,6-dimethylbenzofuran-2(3H)-one

Conditions
ConditionsYield
Multi-step reaction with 7 steps
1: 95 percent / NaOH / 1 h / 120 °C
2: 66 percent / KI; I2; NaHCO3 / H2O / 5 h / 20 °C
3: 82 percent / DBU / tetrahydrofuran / 3 h / Heating
4: 87 percent / CuBr*Me2S / tetrahydrofuran / 12 h / -10 °C
5: 60 percent / KI; I2; NaHCO3 / tetrahydrofuran; H2O / 2 h / 20 °C
6: 92 percent / DBU / tetrahydrofuran / 2 h / Heating
7: 79 percent / LDA / tetrahydrofuran / 1.5 h / -78 °C
View Scheme
34939-28-1, 78601-28-2, 138258-79-4, 78601-26-0

dimethyl 2-(cyclohex-2-en-1-yl)propanedioate

182699-77-0

(-)-(3aS,3aS,7aR)-3a,4,5,7a-tetrahydro-3,6-dimethylbenzofuran-2(3H)-one

Conditions
ConditionsYield
Multi-step reaction with 8 steps
1: 74 percent / NaCl / H2O; dimethylsulfoxide / 24 h / 160 °C
2: 95 percent / NaOH / 1 h / 120 °C
3: 66 percent / KI; I2; NaHCO3 / H2O / 5 h / 20 °C
4: 82 percent / DBU / tetrahydrofuran / 3 h / Heating
5: 87 percent / CuBr*Me2S / tetrahydrofuran / 12 h / -10 °C
6: 60 percent / KI; I2; NaHCO3 / tetrahydrofuran; H2O / 2 h / 20 °C
7: 92 percent / DBU / tetrahydrofuran / 2 h / Heating
8: 79 percent / LDA / tetrahydrofuran / 1.5 h / -78 °C
View Scheme
  • Display:default sort

    New supplier

  • 3A,4,5,7A-TETRAHYDRO-3,6-DIMETHYLBENZOFURAN-2(3H)-ONE CAS:182699-77-0

  • Casno:

    182699-77-0

    3A,4,5,7A-TETRAHYDRO-3,6-DIMETHYLBENZOFURAN-2(3H)-ONE CAS:182699-77-0

    Min.Order: 1 Gram

    FOB Price:  USD $ 0.0-0.0

    3A,4,5,7A-TETRAHYDRO-3,6-DIMETHYLBENZOFURAN-2(3H)-ONE CAS:182699-77-0 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, special

    Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, speciali

  •  Qingdao Beluga Import and Export Co., LTD

     China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:+8613854236000

    Address:qingdao

       Inquiry Now

  • 2(3H)-Benzofuranone,3a,4,5,7a-tetrahydro-3,6-dimethyl-, (3S,3aS,7aR)-

  • Casno:

    182699-77-0

    2(3H)-Benzofuranone,3a,4,5,7a-tetrahydro-3,6-dimethyl-, (3S,3aS,7aR)-

    Min.Order: 1 Kilogram

    FOB Price:  USD $ 0.0-0.0

    Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

    Shandong Hanjiang Chemical Co., Ltd. is located in Qilu Petrochemical Industrial Park, Zibo City, Shandong Province, involving pesticide, medicine, chemical industry, coating, dy

  •  Shandong Hanjiang Chemical Co., Ltd.

     China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:18369939125

    Address:95A, Xingyuan East Road, Zhangdian District

       Inquiry Now

  • 2(3H)-Benzofuranone,3a,4,5,7a-tetrahydro-3,6-dimethyl-, (3S,3aS,7aR)-

  • Casno:

    182699-77-0

    2(3H)-Benzofuranone,3a,4,5,7a-tetrahydro-3,6-dimethyl-, (3S,3aS,7aR)-

    Min.Order: 0

    FOB Price:  USD $ 0.0-0.0

    Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

    The company is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds,

  •  Henan Wentao Chemical Product Co., Ltd.

     China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:+86-370-2722992

    Address:32 Room, 5th Floor, Building 11, No. 6 Yinxing Road, High-tech Industrial Development Zone, Zhengzhou City, Henan Province

       Inquiry Now

  • 2(3H)-Benzofuranone,3a,4,5,7a-tetrahydro-3,6-dimethyl-, (3S,3aS,7aR)-

  • Casno:

    182699-77-0

    2(3H)-Benzofuranone,3a,4,5,7a-tetrahydro-3,6-dimethyl-, (3S,3aS,7aR)-

    Min.Order: 10 Gram

    FOB Price:  USD $ 100.0-100.0

    Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

    Hangyu Biotech is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and O

  •  Zibo Hangyu Biotechnology Development Co., Ltd

    China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:86-15965530500

    Address:Room1701, Tianxing Building,Licheng district, jinan, Shandong, China

       Inquiry Now

  • 2(3H)-Benzofuranone,3a,4,5,7a-tetrahydro-3,6-dimethyl-, (3S,3aS,7aR)-

  • Casno:

    182699-77-0

    2(3H)-Benzofuranone,3a,4,5,7a-tetrahydro-3,6-dimethyl-, (3S,3aS,7aR)-

    Min.Order: 0

    FOB Price:  USD $ 0.0-0.0

    1.Our services:A.Supply sampleB.The packing also can be according the customers` requirmentC.Any inquiries will be replied within 24 hoursD.we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate.

    Our company engages in Electronic chemicals such as OLED,Photoresist chemical,Electrolyte additive and Intermediate Pharmaceutical production; development of noble metal catalysts,

  •  Henan Tianfu Chemical Co., Ltd.

     China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:86-371-55170693/55170694

    Address:Zhengzhou International Trade New Territory,Jinshui District,Zhengzhou ,China

       Inquiry Now

  • 2(3H)-Benzofuranone,3a,4,5,7a-tetrahydro-3,6-dimethyl-, (3S,3aS,7aR)-

  • Casno:

    182699-77-0

    2(3H)-Benzofuranone,3a,4,5,7a-tetrahydro-3,6-dimethyl-, (3S,3aS,7aR)-

    Min.Order: 0

    FOB Price:  USD $ 0.0-0.0

    Ansciep Chemical is a professional enterprise manufacturing and distributing fine chemicals and speciality chemicals. We have been dedicated to heterocycle compounds and phenyl rings for tens of years. This is our mature product for export. Our quali

    Antimex Chemical Limied, was founded in 2001, we are specializing in manufacturing & researching of Active pharmaceutical Ingredients,Veterinary pharm APIs,cosmetic ingredients,and

  •  Antimex Chemical Limied

    China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:0086-21-50563169

    Address:Room1027,No.Jinyu Road,Pudong

       Inquiry Now

  • 3A,4,5,7A-TETRAHYDRO-3,6-DIMETHYLBENZOFURAN-2(3H)-ONE

  • Casno:

    182699-77-0

    3A,4,5,7A-TETRAHYDRO-3,6-DIMETHYLBENZOFURAN-2(3H)-ONE

    Min.Order: 0

    FOB Price:  USD $ 0.0-0.0

    3A,4,5,7A-TETRAHYDRO-3,6-DIMETHYLBENZOFURAN-2(3H)-ONEAppearance:white crystalline powder Storage:Store in dry, dark and ventilated place Package:25KG drum Application:intermediate Transportation:by air, by sea, by express

    Welcome to Hangzhou Fandachem Co.,Ltd (www.FandaChem.com) Hangzhou Fandachem Co.,Ltd (Fandachem),an experienced and professional China-based Fine Chemical supplier. We supply the

  •  Hangzhou Fandachem Co.,Ltd

    China (Mainland)  |  Contact Details

    Business Type:Other

    Tel:+86-571-28800458

    Address:Room 5010, No.9 YanAn Road,Hangzhou,Zhejiang,China

       Inquiry Now

  • 3A,4,5,7A-TETRAHYDRO-3,6-DIMETHYLBENZOFURAN-2(3H)-ONE

  • Casno:

    182699-77-0

    3A,4,5,7A-TETRAHYDRO-3,6-DIMETHYLBENZOFURAN-2(3H)-ONE

    Min.Order: 0

    FOB Price:  USD $ 0.0-0.0

    factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin

    Henan Kanbei Chemical Co., Ltd. is a modern high-tech chemical enterprise integrating R&D, production and sales. The company has strong technical strength, advanced equipment, stri

  •  Henan Kanbei Chemical Co.,LTD

    China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:86-152-37804566

    Address:Evergrande Future City, intersection of Zhengkai Avenue and Sixteenth Street, Kaifeng Area, Henan Pilot Free Trade Zone

       Inquiry Now

  • 182699-77-0

  • Casno:

    182699-77-0

    182699-77-0

    Min.Order: 0

    FOB Price:  USD $ 0.0-0.0

    Good Quality Package:1kg/bag Application:Medical or chemical Transportation:Air/Train/Sea Port:Shenzhen

    Shanghai Chinqesen Biotechnology Co., Ltd. Company slogan:?Innovation, cooperation and win-win Company introduction:?Shanghai Chinqesen Biotechnology Co., Ltd. is a professional ph

  •  Shanghai Chinqesen Biotechnology Co., Ltd.

    China (Mainland)  |  Contact Details

    Business Type:Trading Company

    Tel:+8617316470195

    Address:333 Songze Avenue, Qingpu District, Shanghai

       Inquiry Now

  • 3A,4,5,7A-TETRAHYDRO-3,6-DIMETHYLBENZOFURAN-2(3H)-ONE

  • Casno:

    182699-77-0

    3A,4,5,7A-TETRAHYDRO-3,6-DIMETHYLBENZOFURAN-2(3H)-ONE

    Min.Order: 0

    FOB Price:  USD $ 0.0-0.0

    factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin

    Zhejiang Jiuzhou Chemical Co.,Ltd is a market-oriented and innovation-driven biopharmaceutical company. The company is focusing on the R&D, manufacturing and sales of pharmaceutica

  •  ZHEJIANG JIUZHOU CHEM CO.,LTD

    China (Mainland)  |  Contact Details

    Business Type:Trading Company

    Tel:+86 19334956669

    Address:Waisha Road,Jiaojiang

       Inquiry Now

  • 2(3H)-Benzofuranone,3a,4,5,7a-tetrahydro-3,6-dimethyl-, (3S,3aS,7aR)-

  • Casno:

    182699-77-0

    2(3H)-Benzofuranone,3a,4,5,7a-tetrahydro-3,6-dimethyl-, (3S,3aS,7aR)-

    Min.Order: 0

    FOB Price:  USD $ 0.0-0.0

    United Scientific Company Located in Shanghai of China , is a competitive player in the global specialty and fine chemical market. Fenghua has both the expertise and flexibility to produce a wide range of chemicals. Focusing on developing the innovat

    United Scientific Company (USC) Located in Shanghai of China , is a competitive player in the global specialty and fine chemical market. USC has both the expertise and flexibility

  • Shanghai united Scientific Co.,Ltd.

    China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:+86-21-53535353

    Address:28F No.900 huaihai Road Shanghai China

       Inquiry Now

  • 3,6-dimethyl-3,3a,4,5-tetrahydrobenzofuran-2(7ah)-one

  • Casno:

    182699-77-0

    3,6-dimethyl-3,3a,4,5-tetrahydrobenzofuran-2(7ah)-one

    Min.Order: 0

    FOB Price:  USD $ 0.0-0.0

    We did before and have a mature technology.If you need NMR/HPLC,please contact with us Package:As your requrement Application:Intermediate Transportation:By Express

    Hopschain Chemical Co. founded in 2010 is one of the most professional laboratory and manufactory of intermediate products in China. As a young company, Hopschain Chemical always b

  • Changzhou Hopschain Chemical Co.,Ltd

    China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:86-519-85528066

    Address:Room 710, Unit A, Xingbei Development Mansion, Tongjiang Road, Changzhou City,213000, China

       Inquiry Now

  • 2(3H)-Benzofuranone,3a,4,5,7a-tetrahydro-3,6-dimethyl-, (3S,3aS,7aR)-

  • Casno:

    182699-77-0

    2(3H)-Benzofuranone,3a,4,5,7a-tetrahydro-3,6-dimethyl-, (3S,3aS,7aR)-

    Min.Order: 0

    FOB Price:  USD $ 0.0-0.0

    2(3H)-Benzofuranone,3a,4,5,7a-tetrahydro-3,6-dimethyl-, (3S,3aS,7aR)-Appearance:Off white to slight yellow solid Storage:keep in dry and cool condition Package:25kg or according to cutomer's demand Application:Chemical research/pharma intermediate Tr

    Nanjing Raymon Biotech Co., Ltd. is specialized in developing and marketing middle & high level pharmaceutical intermediates. We are supplying different categories of high-quality

  • Nanjing Raymon Biotech Co., Ltd.

     China (Mainland)  |  Contact Details

    Business Type:Trading Company

    Tel:86-025-52181296

    Address:Block B, No. 918, Shuanglong Avenue

       Inquiry Now

  • 182699-77-0

  • Casno:

    182699-77-0

    182699-77-0

    Min.Order: 0

    FOB Price:  USD $ 0.0-0.0

    Supply top quality products with a reasonable price Application:api

    Hebei Ruishun Trade Co.,Ltd registered capital one million, we have a production of pharmaceutical raw materials, pharmaceutical raw materials factory reagent r&d center, we do

  • Hebei Ruishun Trade Co.,Ltd

    China (Mainland)  |  Contact Details

    Business Type:Trading Company

    Tel:+86-311-68037669

    Address:WanDa commerce building ,yuhua district

       Inquiry Now

  • Total:15 Page 1 of 1 1
Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 182699-77-0