CAS No.22952-87-0,(5alpha,6beta)-6-azido-4,5-epoxy-17-methylmorphinan-3-ol Suppliers

Products Categories

Pharmaceutical (8)
Others (3)
Organic Chemicals (1)

Basic Information

Molecular Structure:
CAS No.:	22952-87-0
Name:	(5alpha,6beta)-6-azido-4,5-epoxy-17-methylmorphinan-3-ol
Article Data:	4

Formula:	C17H20 N4 O2
Molecular Weight:	312.371
Synonyms:	Morphinan-3-ol,6b-azido-4,5a-epoxy-17-methyl- (8CI);Azidomorphine;
EINECS:	245-349-1
Density:	g/cm³
Boiling Point:	°Cat760mmHg
Flash Point:	°C
Safety:	Poison by ingestion, subcutaneous, and intravenous routes. When heated to decomposition it emits toxic fumes of NO_x. See also AZIDES and MORPHINE HYDROCHLORIDE; MORPHINE METHOCHLORIDE; MORPHINE MONOHYDRATE; MORPHINE SULFATE.

Country:
Business Type:
All

Lab/Research institutions

Trading Company

Manufacturers

Other
Certificate:
Manufacturer

Enterprise Authentication

ISO

GMP

FDA

HALAL

Display:default sort
Suppiers of more reward points first

New supplier

Total:12 Page 1 of 1 1

Post a RFQ

Cas No.:

Product Name:

Quantity:

Email:

Company name:

Valid Period:

Detailed Requirements:

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

What can I do for you?
Get Best Price

Get Best Price for 22952-87-0

Chemistry

Molecular Formula: C₁₇H₂₀N₄O₂
Molar mass: 312.3663 g/mol
EINECS: 245-349-1
Product categories of Azidomorphine (22952-87-0):Toxicant
Structure of Azidomorphine (22952-87-0):

XLogP3-AA: 3.4
H-Bond Donor: 1
H-Bond Acceptor: 5
SMILES: [N-]=[N+]=N\[C@H]4[C@@H]5Oc1c2c(ccc1O)C[C@H]3N(CC[C@]25[C@H]3CC4)C
InChI: InChI=1/C17H20N4O2/c1-21-7-6-17-10-3-4-11(19-20-18)16(17)23-15-13(22)5-2-9(14(15)17)8-12(10)21/h2,5,10-12,16,22H,3-4,6-8H2,1H3/t10-,11+,12+,16-,17-/m0/s1
InChIKey: KZOKOEQTKWBKOK-XHQKLZHNBX
Std. InChI: InChI=1S/C17H20N4O2/c1-21-7-6-17-10-3-4-11(19-20-18)16(17)23-15-13(22)5-2-9(14(15)17)8-12(10)21/h2,5,10-12,16,22H,3-4,6-8H2,1H3/t10-,11+,12+,16-,17-/m0/s1
Std. InChIKey: KZOKOEQTKWBKOK-XHQKLZHNSA-N

Toxicity Data With Reference

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
mouse	LD50	intravenous	13mg/kg (13mg/kg)		Journal of Pharmacy and Pharmacology. Vol. 27, Pg. 99, 1975.
mouse	LD50	oral	58mg/kg (58mg/kg)		Journal of Pharmacy and Pharmacology. Vol. 27, Pg. 99, 1975.
mouse	LD50	subcutaneous	16mg/kg (16mg/kg)		Journal of Pharmacy and Pharmacology. Vol. 27, Pg. 99, 1975.
rat	LD50	intravenous	8100ug/kg (8.1mg/kg)		Journal of Pharmacy and Pharmacology. Vol. 25, Pg. 929, 1973.
rat	LD50	oral	62mg/kg (62mg/kg)		Journal of Pharmacy and Pharmacology. Vol. 25, Pg. 929, 1973.
rat	LD50	subcutaneous	13mg/kg (13mg/kg)		Journal of Pharmacy and Pharmacology. Vol. 25, Pg. 929, 1973.
rat	LD50	unreported	13mg/kg (13mg/kg)	BEHAVIORAL: ANALGESIA	Pharmacological Research Communications. Vol. 5, Pg. 175, 1973.

Safety Profile

Poison by ingestion, subcutaneous, and intravenous routes. When heated to decomposition it emits toxic fumes of NO_x. See also AZIDES and MORPHINE HYDROCHLORIDE; MORPHINE METHOCHLORIDE; MORPHINE MONOHYDRATE; MORPHINE SULFATE.

Specification

Azidomorphine (22952-87-0) is an opiate analogue that is a derivative of morphine, and also can be called -Deoxy-6-azidodihydroisomorphine ; Morphinan-3-ol, 6.beta.-azido-4,5.alpha.-epoxy-17-methyl- ;and Morphinan-3-ol, 6-azido-4,5-epoxy-17-methyl-, (5.alpha.,6.beta.)- . It has similar effects to other opioid agonists including analgesia, sedation and respiratory depression. However its addiction liability has been found to be slightly lower than that of morphine in animal studies.