Products Categories
CAS No.: | 23779-99-9 |
---|---|
Name: | floctafenine |
Article Data: | 4 |
Molecular Structure: | |
Formula: | C20H17 F3 N2 O4 |
Molecular Weight: | 406.361 |
Synonyms: | Anthranilicacid, N-[8-(trifluoromethyl)-4-quinolyl]-, 2,3-dihydroxypropyl ester (8CI);Glycerol, 1-[N-[8-(trifluoromethyl)-4-quinolyl]anthranilate] (8CI); Diralgan;Floctafenin; Floctafenine; Idalon; Idarac; Novodolan; R 4138; R 4318; RU 15750 |
Density: | 1.437g/cm3 |
Melting Point: | 179-180° |
Boiling Point: | 592.1°C at 760 mmHg |
Flash Point: | 311.9°C |
Safety: | Poison by intravenous and intraperitoneal routes. Moderately toxic by ingestion. An experimental teratogen. Experimental reproductive effects. When heated to decomposition it emits very toxic fumes of F− and NOx. Used as an analgesic. |
PSA: | 91.68000 |
LogP: | 3.58020 |
1. | orl-rat LD50:535 mg/kg | YACHDS Yakuri to Chiryo. Pharmacology and Therapeutics. 9 (Suppl 2)(1981),299. | ||
2. | ipr-rat LD50:250 mg/kg | YACHDS Yakuri to Chiryo. Pharmacology and Therapeutics. 9 (Suppl 2)(1981),299. | ||
3. | ivn-rat LD50:160 mg/kg | TXAPA9 Toxicology and Applied Pharmacology. 36 (1976),173. | ||
4. | orl-mus LD50:1960 mg/kg | YACHDS Yakuri to Chiryo. Pharmacology and Therapeutics. 9 (Suppl 2)(1981),299. | ||
5. | ipr-mus LD50:245 mg/kg | TXAPA9 Toxicology and Applied Pharmacology. 36 (1976),173. | ||
6. | ivn-mus LD50:180 mg/kg | TXAPA9 Toxicology and Applied Pharmacology. 36 (1976),173. | ||
7. | orl-rbt LD50:700 mg/kg | TXAPA9 Toxicology and Applied Pharmacology. 36 (1976),173. |