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23779-99-9

Basic Information
CAS No.: 23779-99-9
Name: floctafenine
Article Data: 4
Molecular Structure:
Molecular Structure of 23779-99-9 (floctafenine)
Formula: C20H17 F3 N2 O4
Molecular Weight: 406.361
Synonyms: Anthranilicacid, N-[8-(trifluoromethyl)-4-quinolyl]-, 2,3-dihydroxypropyl ester (8CI);Glycerol, 1-[N-[8-(trifluoromethyl)-4-quinolyl]anthranilate] (8CI); Diralgan;Floctafenin; Floctafenine; Idalon; Idarac; Novodolan; R 4138; R 4318; RU 15750
Density: 1.437g/cm3
Melting Point: 179-180°
Boiling Point: 592.1°C at 760 mmHg
Flash Point: 311.9°C
Safety: Poison by intravenous and intraperitoneal routes. Moderately toxic by ingestion. An experimental teratogen. Experimental reproductive effects. When heated to decomposition it emits very toxic fumes of F and NOx. Used as an analgesic.
PSA: 91.68000
LogP: 3.58020
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Toxicity Data With Reference

1.   

orl-rat LD50:535 mg/kg

    YACHDS    Yakuri to Chiryo. Pharmacology and Therapeutics. 9 (Suppl 2)(1981),299.
2.   

ipr-rat LD50:250 mg/kg

    YACHDS    Yakuri to Chiryo. Pharmacology and Therapeutics. 9 (Suppl 2)(1981),299.
3.   

ivn-rat LD50:160 mg/kg

    TXAPA9    Toxicology and Applied Pharmacology. 36 (1976),173.
4.   

orl-mus LD50:1960 mg/kg

    YACHDS    Yakuri to Chiryo. Pharmacology and Therapeutics. 9 (Suppl 2)(1981),299.
5.   

ipr-mus LD50:245 mg/kg

    TXAPA9    Toxicology and Applied Pharmacology. 36 (1976),173.
6.   

ivn-mus LD50:180 mg/kg

    TXAPA9    Toxicology and Applied Pharmacology. 36 (1976),173.
7.   

orl-rbt LD50:700 mg/kg

    TXAPA9    Toxicology and Applied Pharmacology. 36 (1976),173.

Safety Profile

Poison by intravenous and intraperitoneal routes. Moderately toxic by ingestion. An experimental teratogen. Experimental reproductive effects. When heated to decomposition it emits very toxic fumes of F and NOx. Used as an analgesic.