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2571-86-0

Basic Information
CAS No.: 2571-86-0
Name: Coriamyrtin
Article Data: 3
Molecular Structure:
Molecular Structure of 2571-86-0 (Coriamyrtin)
Formula: C15H18 O5
Molecular Weight: 278.305
Synonyms: Coriamyrtin(6CI,7CI);Spiro[2,5-methano-7H-oxireno[3,4]cyclopent[1,2-d]oxepin-7,2'-oxiran]-3(2H)-one,hexahydro-1b-hydroxy-6a-methyl-8-(1-methylethenyl)-, [1aS-(1aa,1bb,2b,5b,6ab,7b,7aa,8S*)]-;Spiro[2,5-methano-7H-oxireno[3,4]cyclopent[1,2-d]oxepin-7,2'-oxiran]-3(2aH)-one, 1ab,1b,5a,6,6a,7ab-hexahydro-1ba-hydroxy-8a-isopropenyl-6aa-methyl- (8CI); (+)-Coriamyrtin;Coriamyrtine
Density: 1.43g/cm3
Melting Point: 229-230°
Boiling Point: 485.9°Cat760mmHg
Flash Point: 187.3°C
Safety: Poison by subcutaneous, intravenous, intraperitoneal, and possibly other routes. When heated to decomposition it emits acrid smoke and fumes.
PSA: 71.59000
LogP: 0.41140
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Chemistry

Product Name: Coriamyrtin
Synonyms of Coriamyrtin (CAS NO:2571-86-0) : Coriamyrtine ; Coriamyrtione ; Spiro(2,5-methano-7H-oxireno(3,4)cyclopent(1,2-d)oxepin-7,2'-oxiran)-3(2H)-one, hexahydro-1b-hydroxy-6a-methyl-8-(1-methylethenyl)-, (1aS-(1aalpha,1bbeta,2beta,5beta,6abeta,7beta,7aalpha,8S*))- (9CI) 
InChI: InChI=1/C15H18O5/c1-6(2)8-7-4-13(3)14(5-18-14)10-11(20-10)15(13,17)9(8)12(16)19-7/h7-11,17H,1,4-5H2,2-3H3/t7-,8+,9+,10+,11-,13-,14+,15-/m0/s1
Classification Code :Drug / Therapeutic Agent ;Natural Product
CAS NO:2571-86-0
Molecular Formula:C15H18O5
Molecular Weight :278.3004
Molecular Structure :
EINECS: 244-880-6
Index of Refraction: 1.611
Surface Tension: 55.3 dyne/cm
Density: 1.43 g/cm3
Flash Point: 187.3 °C
Enthalpy of Vaporization: 86.59 kJ/mol
Boiling Point: 485.9 °C at 760 mmHg
Vapour Pressure: 1.76E-11 mmHg at 25°C 
Melting point: 229 ~ 230°C
Solubility: Coriamyrtin (CAS NO:2571-86-0) is slightly soluble in water and anhydrous ethanol, soluble in hot ethanol.

Uses

 Coriamyrtin (CAS NO:2571-86-0) has central excitatory effect.

Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
cat LDLo unreported 237ug/kg (0.237mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD Journal of Pharmacology and Experimental Therapeutics. Vol. 57, Pg. 361, 1936.
frog LDLo subcutaneous 10mg/kg (10mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD Journal of Pharmacology and Experimental Therapeutics. Vol. 57, Pg. 410, 1936.
guinea pig LDLo subcutaneous 2439ug/kg (2.439mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD Journal of Pharmacology and Experimental Therapeutics. Vol. 57, Pg. 361, 1936.
mouse LD50 intraperitoneal 3mg/kg (3mg/kg)   Journal of Medicinal Chemistry. Vol. 11, Pg. 729, 1968.
mouse LD50 subcutaneous 3234ug/kg (3.234mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD Journal of the American Pharmaceutical Association, Scientific Edition. Vol. 29, Pg. 2, 1940.
mouse LDLo intravenous 1mg/kg (1mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD Journal of Pharmacology and Experimental Therapeutics. Vol. 57, Pg. 410, 1936.
rabbit LD50 intravenous 371ug/kg (0.371mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD Journal of the American Pharmaceutical Association, Scientific Edition. Vol. 29, Pg. 2, 1940.
rabbit LD50 subcutaneous 930ug/kg (0.93mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD Journal of the American Pharmaceutical Association, Scientific Edition. Vol. 29, Pg. 2, 1940.
rat LDLo intravenous 700ug/kg (0.7mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD Journal of Pharmacology and Experimental Therapeutics. Vol. 57, Pg. 410, 1936.
rat LDLo subcutaneous 1mg/kg (1mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD Journal of Pharmacology and Experimental Therapeutics. Vol. 57, Pg. 410, 1936.

Safety Profile

Poison by subcutaneous, intravenous, intraperitoneal, and possibly other routes. When Coriamyrtin (CAS NO:2571-86-0) is heated to decomposition, it emits acrid smoke and fumes.