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26717-47-5

Basic Information
CAS No.: 26717-47-5
Name: clofibride
Article Data: 4
Molecular Structure:
Molecular Structure of 26717-47-5 (clofibride)
Formula: C16H22 Cl N O4
Molecular Weight: 327.808
Synonyms: Propionicacid, 2-(p-chlorophenoxy)-2-methyl-, ester with 4-hydroxy-N,N-dimethylbutyramide(8CI); Butyramide, 4-hydroxy-N,N-dimethyl-,2-(p-chlorophenoxy)-2-methylpropionate (ester) (8CI);4-Hydroxy-N,N-dimethylbutyramide 4-chlorophenoxyisobutyrate; Clofibride;Lipenan; MG 46
Density: 1.163g/cm3
Melting Point: 34°C
Boiling Point: 448.7°Cat760mmHg
Flash Point: 225.2°C
Safety: Moderately toxic by ingestion and intraperitoneal routes. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of Cl and NOx.
PSA: 55.84000
LogP: 2.90900
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  • Propanoic acid,2-(4-chlorophenoxy)-2-methyl-, 4-(dimethylamino)-4-oxobutyl ester

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    Propanoic acid,2-(4-chlorophenoxy)-2-methyl-, 4-(dimethylamino)-4-oxobutyl ester

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  • Propanoic acid,2-(4-chlorophenoxy)-2-methyl-, 4-(dimethylamino)-4-oxobutyl ester

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    Propanoic acid,2-(4-chlorophenoxy)-2-methyl-, 4-(dimethylamino)-4-oxobutyl ester

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Chemistry

IUPAC Name: [4-(Dimethylamino)-4-oxobutyl] 2-(4-chlorophenoxy)-2-methylpropanoate
Synonyms: 2-(4-Chlorophenoxy)-2-methylpropanoic Acid 4-(Dimethylamino)-4-oxobutyl Ester ; 4-(Dimethylamino)-4-oxobutyl 2-(4-chlorophenoxy)-2-methylpropanoate ; 4-(Dimethylamino)-4-oxobutyl 2-[(4-chlorophenyl)oxy]-2-methylpropanoate ; Clofibride ;propanoic acid, 2-(4-chlorophenoxy)-2-methyl-, 4-(dimethylamino)-4-oxobutyl ester ; Propionic acid, 2-(4-chlorophenoxy)-2-methyl-, 4-(dimethylamino)-4-oxobutyl ester (9CI)
Molecular Formula of Lipenan (CAS NO.26717-47-5) : C16H22ClNO4
Molecular Weight of Lipenan (CAS NO.26717-47-5) : 327.8032
Molecular Structure of Lipenan (CAS NO.26717-47-5) :
CAS NO: 26717-47-5
Index of Refraction: 1.515
Surface Tension: 39.9 dyne/cm
Density: 1.163 g/cm3
Flash Point: 225.2 °C
Enthalpy of Vaporization: 70.73 kJ/mol
Boiling Point: 448.7 °C at 760 mmHg
Vapour Pressure: 3.04E-08 mmHg at 25°C

Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 960mg/kg (960mg/kg) BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY)

LUNGS, THORAX, OR RESPIRATION: CYANOSIS

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION
Journal Europeen de Toxicologie. Vol. 5, Pg. 239, 1972.
mouse LD50 oral 1080mg/kg (1080mg/kg) BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY)

LUNGS, THORAX, OR RESPIRATION: CYANOSIS

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION
Journal Europeen de Toxicologie. Vol. 5, Pg. 239, 1972.
rat LD50 intraperitoneal 1175mg/kg (1175mg/kg) BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY)

LUNGS, THORAX, OR RESPIRATION: CYANOSIS

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION
Journal Europeen de Toxicologie. Vol. 5, Pg. 239, 1972.
rat LD50 oral 2485mg/kg (2485mg/kg) BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY)

LUNGS, THORAX, OR RESPIRATION: CYANOSIS

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION
Journal Europeen de Toxicologie. Vol. 5, Pg. 239, 1972.

 

 

Safety Profile

Moderately toxic by ingestion and intraperitoneal routes. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of Cl and NOx.